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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Discrimination between active and inactive neurocysticercosis by metacestode excretory/secretory antigens of Taenia solium in an enzyme-linked immunosorbent assay.
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Discrimination between active and inactive neurocysticercosis by metacestode excretory/secretory antigens of Taenia solium in an enzyme-linked immunosorbent assay.

机译：在酶联免疫吸附试验中，通过Ta虫的meta虫的分泌/分泌抗原区分活动性和非活动性神经囊尾rc病。

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摘要

To detect IgG antibodies to Taenia solium, a controlled double-blind study was conducted using 91 coded cerebrospinal fluid samples from patients with neurocysticercosis (NCC) and other neurologic disorders. Samples were tested in an enzyme-linked immunosorbent assay (ELISA) using metacestode excretion/secretion antigens. The results were correlated with data from medical records on the diagnosis of NCC (based on computed tomography and magnetic resonance imaging criteria) and other neurologic disorders. The ELISA results were positive in 22 of the 24 cases with active NCC. In contrast, six cases with calcified cysts (inactive NCC), as well as one case in a transitional stage, were negative. One case with a calcified granuloma and another with a granuloma plus calcifications (classified as inactive NCC) had positive results. The remaining negative results corresponded to other neurologic disorders (58 cases). The results of the ELISA showed a significant difference between active and inactive NCC (P = 0.0034).
机译：为了检测针对牛带en虫的IgG抗体，我们使用来自神经囊尾study病（NCC）和其他神经系统疾病患者的91个编码的脑脊髓液样本进行了对照双盲研究。使用前肠排泄/分泌抗原在酶联免疫吸附测定（ELISA）中测试样品。结果与来自NCC诊断的医学记录数据（基于计算机断层扫描和磁共振成像标准）和其他神经系统疾病相关。 24例活动性NCC患者中有22例ELISA结果呈阳性。相比之下，有6例钙化囊肿（无效的NCC）以及1例处于过渡期的病例均为阴性。一例伴钙化肉芽肿，另一例伴肉芽肿伴钙化（分类为非活动性NCC）有阳性结果。其余阴性结果对应于其他神经系统疾病（58例）。 ELISA结果显示，活跃和不活跃的NCC之间存在显着差异（P = 0.0034）。

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