Haemophilus influenzae type B meningitis among children in Hanoi, Vietnam: epidemiologic patterns and estimates of H. Influenzae type B disease burden.

Anh DD; Kilgore PE; Kennedy WA; Nyambat B; Long HT; Jodar L; Clemens JD; Ward JI

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Haemophilus influenzae type B meningitis among children in Hanoi, Vietnam: epidemiologic patterns and estimates of H. Influenzae type B disease burden.

机译：越南河内儿童中的B型流感嗜血杆菌脑膜炎：流行病学模式和H. B型流感疾病负担估计值。

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From March 2000 to February 2002, a population-based study of Haemophilus influenzae type b (Hib) meningitis was conducted among children less than five years of age in Hanoi, Vietnam. Children with suspected bacterial meningitis were referred to hospitals and each patient underwent standardized clinical examination and microbiologic testing. In Hanoi, 580 children were evaluated for bacterial meningitis and 23 (4%) had confirmed or probable Hib meningitis. The incidence of all Hib meningitis was 12/100,000 child-years less than five years of age and 26/100,000 child-years less than two years of age. Nationally, an estimated 1,005 children less than five years of age are hospitalized for Hib meningitis and 5,107 are hospitalized for Hib pneumonia. Among children with Hib meningitis, at least 100 will develop severe neurologic sequelae and 40 will die. These data suggest there is a substantial burden of Hib disease in Vietnam. National leaders will be provided with these data to facilitate development of national vaccination policies for children in Vietnam.

机译：从2000年3月至2002年2月，在越南河内对5岁以下的儿童进行了b型流感嗜血杆菌（Hib）脑膜炎人群研究。怀疑患有细菌性脑膜炎的儿童被转诊至医院，每位患者均接受了标准化的临床检查和微生物学检测。在河内，对580名儿童进行了细菌性脑膜炎评估，其中23名（4％）确诊或可能患有Hib脑膜炎。所有Hib脑膜炎的发病率均在5岁以下12 / 100,000儿童年和2岁以下26 / 100,000儿童年。在全国范围内，估计有1,005名五岁以下儿童因Hib脑膜炎住院，有5,107名儿童因Hib肺炎住院。在患有Hib脑膜炎的儿童中，至少有100人会出现严重的神经系统后遗症，其中40人会死亡。这些数据表明，越南有严重的Hib疾病负担。将为国家领导人提供这些数据，以促进制定针对越南儿童的国家疫苗接种政策。

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来源
《The American Journal of Tropical Medicine and Hygiene》 |2006年第3期|共7页
作者
Anh DD; Kilgore PE; Kennedy WA; Nyambat B; Long HT; Jodar L; Clemens JD; Ward JI;
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正文语种 eng
中图分类预防医学、卫生学;
关键词
Haemophilus influenzae type b; Meningitis; Haemophilus; 嗜血菌; 流感; b型; 脑膜炎; 嗜血杆菌;

机译：Haemophilus influenzae type b;Meningitis;Haemophilus;嗜血菌;流感;b型;脑膜炎;嗜血杆菌;

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1. Haemophilus influenzae type B meningitis among children in Hanoi, Vietnam: epidemiologic patterns and estimates of H. Influenzae type B disease burden. [J] . Anh DD, Kilgore PE, Kennedy WA, The American Journal of Tropical Medicine and Hygiene . 2006,第3期

机译：越南河内儿童中的B型流感嗜血杆菌脑膜炎：流行病学模式和H. B型流感疾病负担估计值。
2. Non-type b Haemophilus influenzae disease: clinical and epidemiologic characteristics in the Haemophilus influenzae type b vaccine era. [J] . Heath PT, Booy R, Azzopardi HJ, The Pediatric infectious disease journal . 2001,第3期

机译：非b型流感嗜血杆菌疾病：b型流感嗜血杆菌疫苗时代的临床和流行病学特征。
3. Changes in serotype distribution of Haemophilus influenzae meningitis isolates identified through laboratory-based surveillance following routine childhood vaccination against H. influenzae type b in Brazil. [J] . Zanella RC, Bokermann S, Andrade AL, Vaccine . 2011,第48期

机译：在巴西常规接种儿童乙型流感嗜血杆菌疫苗后，通过实验室监测确定了流感嗜血杆菌脑膜炎分离株血清型分布的变化。
4. A LIQUID STABLE BIOLOGICAL ACTIVE SEMI-SYNTHETIC GLYCOCONJUGATE VACCINE AGAINST HAEMOPHILUS INFLUENZAE TYPE b [C] . Madhu Emmadi, Marilda P. Lisboa, Bopanna Monnanda International Carbohydrate Symposium . 2018

机译：一种液体稳定的生物活性半合成糖醌疫苗，对嗜血杆菌流感型B型
5. Stabilization of the hydrolysis of Haemophilus influenzae type b antigen by aluminum hydroxide adjuvant. [D] . Wittayanukulluk, Arunee. 2002

机译：氢氧化铝佐剂可稳定b型流感嗜血杆菌的水解。
6. Comparative Molecular Analysis of Haemophilus influenzae Isolates from Young Children with Acute Lower Respiratory Tract Infections and Meningitis in Hanoi Vietnam [O] . Hiroshi Watanabe, Chiharu Kaji, Dang Duc Anh, 2005

机译：越南河内患有急性下呼吸道感染和脑膜炎的幼儿流感嗜血杆菌分离株的分子比较分析
7. Tendência das meningites por Haemophilus influenzae tipo b no Brasil, em menores de 5 anos, no período de 1983 a 2002 Trends in Haemophilus influenzae type b meningitis in Brazil in children under five years of age from 1983 through 2002 [O] . Sybelle de Souza Castro Miranzi, Suzana Alves de Moraes, Isabel Cristina Martins de Freitas 2006

机译：自1983年至2002年，巴西5岁以下儿童因B型流感嗜血杆菌引起的脑膜炎趋势1983年至2002年以来巴西5岁以下儿童对B型流感嗜血杆菌脑膜炎的趋势
8. Parenteral Aztreonam in the Treatment of Haemophilus influenzae Type B Meningitis in Egyptian Children. (Reannouncement with New Availability Information). [R] . Girgis, N. I., Abu El Ella, A. H., Farid, Z., 1988

机译：肠外阿兹特罗姆治疗埃及儿童B型流感嗜血杆菌炎。（重新公布新的可用性信息）。

Haemophilus influenzae type B meningitis among children in Hanoi, Vietnam: epidemiologic patterns and estimates of H. Influenzae type B disease burden.

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