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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Hepatitis delta virus infection in mongolia: analyses of geographic distribution, risk factors, and disease severity.
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Hepatitis delta virus infection in mongolia: analyses of geographic distribution, risk factors, and disease severity.

机译：蒙古的三角洲肝炎病毒感染：地理分布，危险因素和疾病严重性分析。

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摘要

The prevalence and risk factors for hepatitis delta virus (HDV) infection among Mongolian school children were assessed by detecting the antibody against HDV and HDV RNA, and through structured interviews. The study subjects consisted of 181 children with the past or ongoing hepatitis B virus infection who were investigated during the nationwide serosurvey conducted in 2004. The prevalence of antibody to HDV was 6.1%, with the proportion of 13.6% among hepatitis B surface antigen (HBsAg)-positive subjects, all of whom had HDV RNA. Multivariate logistic regression analyses showed that injections (> 11 times) (odds ratio [OR] = 8.31, 95% confidence interval [CI] = 1.28-54.07) and blood sampling (> 3 times) (OR 5.34, 95% CI times) (OR = 6.20, 95% CI = 1.18-32.71), and cohabitating with patients with chronic hepatitis (OR = 4.57, 95% CI = 1.26-16.55) predicted the seropositivity for antibody to HDV. These results suggest that parenteral exposures in health care settings and household transmission are the main routes of HDV transmission among Mongolian children.
机译：通过检测针对HDV和HDV RNA的抗体并通过结构化访谈，评估了蒙古学童中肝炎三角洲病毒（HDV）感染的患病率和危险因素。研究对象包括2004年在全国进行的血清学调查中调查的181名过去或正在进行的乙型肝炎病毒感染的儿童。HDV抗体的患病率为6.1％，在乙型肝炎表面抗原（HBsAg）中占13.6％ ）阳性受试者，所有受试者均具有HDV RNA。多元logistic回归分析显示注射（> 11次）（赔率[OR] = 8.31，95％置信区间[CI] = 1.28-54.07）和血液采样（> 3次）（OR 5.34，95％CI次） （OR = 6.20，95％CI = 1.18-32.71），并与慢性肝炎患者同居（OR = 4.57，95％CI = 1.26-16.55）预测了针对HDV抗体的血清阳性。这些结果表明，在医疗机构和家庭传播中的肠胃外暴露是蒙古儿童中HDV传播的主要途径。

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