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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Usefulness of strongyloides stercoralis serology in the management of patients with eosinophilia
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Usefulness of strongyloides stercoralis serology in the management of patients with eosinophilia

机译：甾体类固醇类血清学在嗜酸性粒细胞增多症患者管理中的作用

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摘要

Strongyloides stercoralis infection is being increasingly diagnosed out of endemic areas. The aim of this study is to evaluate the usefulness of S. stercoralis serology for the management of probable strongyloidiasis in patients presenting with eosinophilia. Overall, 147 patients were included, 89 (60.5%) patients had a positive S. stercoralis serology. Strongyloides stercoralis larvae were detected only in 15 (10.2%) patients. Twenty-eight patients had human immunodeficiency virus infection. Eighty patients received ivermectin 200 mcg/Kg/day for 2 days, and follow-up 6 months after treatment could be performed in 32 patients: 26 (81.3%) patients reached the response to treatment criteria (negative serology 6 months after treatment or when by enzyme-linked immunosorbent assay the optical density ratio of post-treatment to pre-treatment decreased to 0.6), and 11 (34.4%) patients fulfilled the cure criteria (negative serology 6 months after treatment). Strongyloides stercoralis serology is a useful diagnostic tool both in the diagnosis of probable strongyloidiasis and follow-up after treatment.
机译：在地方病地区以外，越来越多地诊断出类固醇类固醇感染。这项研究的目的是评估固醇链球菌血清学在患有嗜酸性粒细胞增多症患者中管理可能的圆线虫病的有用性。总体上，包括147位患者，其中89位（60.5％）患者的固醇葡萄球菌血清学阳性。仅在15例（10.2％）患者中检测到了类固醇幼虫。 28名患者感染了人类免疫缺陷病毒。 80例患者接受伊维菌素200 mcg / Kg /天的治疗，为期2天，对32例患者进行治疗后6个月的随访：32例患者（81.3％）达到了对治疗标准的反应（治疗后6个月或何时血清学阴性）通过酶联免疫吸附测定，治疗后与治疗前的光密度比降低至0.6），并且11例（34.4％）患者达到治愈标准（治疗后6个月血清学阴性）。甾体类固线虫血清学在诊断可能的类虫病和治疗后的随访中都是有用的诊断工具。

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