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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >Potential Animal Reservoirs of Toscana Virus and Coinfections with Leishmania infantum in Turkey
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Potential Animal Reservoirs of Toscana Virus and Coinfections with Leishmania infantum in Turkey

机译：土耳其托斯卡纳病毒的潜在动物储库和婴儿利什曼原虫的共感染

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摘要

Toscana virus (TOSV), a sandfly-borne phlebovirus, is an important agent of human meningoencephalitis in the Mediterranean region, for which vertebrates acting as reservoirs have not yet been determined. This study investigates TOSV and Leishmania infections in dogs, cats, sheep, and goats from Adana and Mersin provinces in southeastern Turkey. TOSV neutralizing antibodies were demonstrated in 40.4% of the dog and 4% of the goat samples. TOSV RNA was detected in 9.9% of the 252 samples that mainly comprise dogs (96%). Thus, canine species can be suggested as the candidate reservoirs of TOSV. Partial sequences revealed the activity of TOSV genotypes A and B. In two dogs presenting with symptoms of canine leishmaniasis, infections of TOSV genotype B and Leishmania infantum have been documented, describing the first report of coinfections with these agents.
机译：托斯卡纳病毒（TOSV）是一种由沙蝇传播的静脉病毒，是地中海地区人类脑膜脑炎的重要病原，尚未确定脊椎动物是否为水库。这项研究调查了土耳其东南部阿达纳和梅尔辛省的狗，猫，绵羊和山羊的TOSV和利什曼原虫感染。在40.4％的狗和4％的山羊样品中证明了TOSV中和抗体。在主要由狗组成的252个样本中，有9.9％检测到TOSV RNA（96％）。因此，可以建议将犬种作为TOSV的候选储集层。部分序列揭示了TOSV基因型A和B的活性。在两只出现犬利什曼病症状的狗中，已记录了TOSV基因型B和婴儿利什曼原虫的感染，这是首次报道了使用这些药物共同感染的报道。

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