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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >First report on Ambisome-associated allergic reaction in two Sudanese leishmaniasis patients.
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First report on Ambisome-associated allergic reaction in two Sudanese leishmaniasis patients.

机译:关于两名苏丹利什曼病患者的歧义相关过敏反应的首次报道。

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摘要

Post kala-azar dermal leishmaniasis (PKDL) and mucosal leishmaniasis (ML) are serious clinical forms of leishmaniasis caused by Leishmania donovani parasites in Sudan. Although pentavalent antimonys are used as the first line of treatment of all clinical forms of leishmaniasis, persistent PKDL and ML patients are treated with liposomal amphotericin B (Ambisome) as a second-line drug. In this work, we report the development of allergic reactions by a PKDL and a ML Sudanese patient to Ambisome. The findings warrant future close supervision of patients to be treated with the drug.
机译:黑热病后皮肤利什曼病(PKDL)和粘膜利什曼病(ML)是苏丹利什曼原虫多诺万尼寄生虫引起的严重的利什曼病临床形式。尽管五价锑被用作所有利什曼病临床形式的一线治疗药物,但持久性PKDL和ML患者则以脂质体两性霉素B(Ambisome)作为二线药物治疗。在这项工作中,我们报告了P​​KDL和ML苏丹患者对Ambisome的过敏反应的发展。该发现保证了将来对要用该药物治疗的患者的密切监督。

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