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Difficult Cases of Pain and Nonpain Symptoms in Intractable Spinal Infections: A Case Series

机译:顽固性脊柱感染的疼痛和非疼痛症状的疑难病例:一个病例系列

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In the modern age of advanced surgical techniques and pharmacologic management, bacterial spinal infections (SIs) can be managed (either eradicated or suppressed) in many hosts. However, the optimal management of SIs may be limited by patient comorbidities, which do not allow for surgical management, or limited by antimicrobial options due to side effects, toxicities, or emerging drug resistance. In these settings, frank and honest discussion regarding risks and benefits of treatment should be pursued, including that the SI may be a terminal illness. In this case series, we present 3 patients who had bacterial SIs whose treatments were limited by the above-mentioned factors. Furthermore, each case presented challenges regarding optimal medical management of somatic and neuropathic pain associated with the SI. ? The Author(s) 2012.
机译:在先进的外科手术技术和药物治疗的现代时代,可以在许多宿主中控制(根除或抑制)细菌性脊柱感染(SI)。但是,SI的最佳治疗可能会受到患者合并症的限制,而合并症不允许进行外科手术治疗,或者由于副作用,毒性或新出现的耐药性而受到抗菌药物选择的限制。在这种情况下,应该就治疗的风险和益处进行坦诚的讨论,包括SI可能是绝症。在本病例系列中,我们介绍了3名患有细菌性SI的患者,这些患者的治疗受到上述因素的限制。此外,每个病例都提出了与SI相关的躯体和神经性疼痛的最佳医学管理的挑战。 ?作者2012。

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