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首页> 外文期刊>The American journal of hospice and palliative care >Deep vein thrombosis (DVT) in advanced cancer patients with lower extremity edema referred for assessment.
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Deep vein thrombosis (DVT) in advanced cancer patients with lower extremity edema referred for assessment.

机译：评估下肢水肿的晚期癌症患者的深静脉血栓形成（DVT）。

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Lower extremity edema is a common complication in advanced cancer patients, and deep vein thrombosis (DVT) is one among many causes. Clinical signs and symptoms are known to be unreliable, and radiographic investigations are often required in diagnosing DVT. A retrospective chart review was conducted on 46 advanced cancer patients with lower extremity edema. Researchers analyzed 52 venous duplex scans to determine the radiographic incidence of DVT the reliability of other clinical signs and symptoms in diagnosing DVT, apart from leg edema, and to assess other potential causes of lower extremity edema and their correlation to DVT. Twenty-three (44 percent) of 52 scans were positive for DVT. The most common presentation of edema in the patients with positive scans was bilateral asymmetric edema (11/23, 48 percent). There was limited documentation of other clinical signs and symptoms suggesting DVT. Other variables such as serum albumin (p = 0.46) and creatinine (p = 0.11) were not statistically differentin patients who had positive and negative scans. Of other potential causes of lower extremity edema, such as previous surgery, radiotherapy, tumor, or lymph node compression, a number of patients had a coexisting DVT with bilateral asymmetric edema as the most common presentation. The results of this study suggest that advanced cancer patients with bilateral asymmetric lower extremity edema of potentially multifactorial origin have a high incidence of DVT.
机译：下肢水肿是晚期癌症患者的常见并发症，深静脉血栓形成（DVT）是许多原因之一。已知临床症状和体征不可靠，诊断DVT时通常需要进行射线照相检查。对46例下肢水肿的晚期癌症患者进行了回顾性图表回顾。研究人员分析了52次静脉双工扫描，以确定DVT的放射学发生率，诊断DVT的其他临床体征和症状（腿部水肿除外）的可靠性，以及评估下肢水肿的其他潜在原因及其与DVT的相关性。 52例扫描中有23例（44％）DVT阳性。扫描阳性的患者中最常见的水肿表现是双侧不对称水肿（11 / 23，48％）。其他提示DVT的临床体征和症状的文献很少。在扫描阳性和阴性的患者中，血清白蛋白（p = 0.46）和肌酐（p = 0.11）等其他变量在统计学上无差异。在其他可能导致下肢水肿的潜在原因中，例如先前的手术，放疗，肿瘤或淋巴结受压，许多患者并发DVT，双侧非对称性水肿是最常见的表现。这项研究的结果表明，患有潜在的多因素起源的双侧非对称性下肢水肿的晚期癌症患者高发DVT。

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