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首页> 外文期刊>The Australasian journal of dermatology >Early melanoma with halo eczema (Meyerson's phenomenon).
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Early melanoma with halo eczema (Meyerson's phenomenon).

机译:早期黑色素瘤伴光晕湿疹(迈尔森现象)。

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摘要

We present a case of a 49-year-old man who presented with a solitary atypical pigmented lesion with a surrounding halo of dermatitis. Dermoscopy showed a pigment network at the periphery with areas of scar-like depigmentation, negative pigment network and erythema. The lesion was treated preoperatively with a potent topical corticosteroid resulting in a reduction of inflammation. Histology showed an early Clark level 1 melanoma arising within a severely dysplastic compound melanocytic naevus. There was an adjacent perivascular chronic inflammatory cell infiltrate with occasional eosinophils. Minimal, though definite spongiosis with parakeratosis was also present. The scar was subsequently re-excised achieving appropriate excision margins for melanoma in situ. Six months later, there was recurrence of dermatitis at the scar with no evidence of recurrent melanoma. To our knowledge, melanoma with Meyerson phenomenon has not been reported in the literature. This case highlights that all lesions should be evaluated on clinical and dermoscopic grounds regardless of the presence or absence of eczema. Our case adds yet another entity that may display Meyerson phenomenon and consequently a halo of eczema cannot be considered a reassuring sign when evaluating melanocytic lesions.
机译:我们介绍了一个49岁的男性患者,该患者患有孤立的非典型色素性病变,并伴有周围的皮炎光环。皮肤镜检查显示周围有色素网,周围有疤痕状色素沉着,色素网阴性和红斑。术前用强效局部糖皮质激素治疗病变,可减轻炎症。组织学显示,在严重发育不良的复合性黑素细胞痣中出现了早期的克拉克1级黑色素瘤。偶尔有嗜酸性粒细胞浸润相邻的血管周围慢性炎症细胞。尽管存在一定程度的海绵状变性和角化不全,但也很少。疤痕随后被切除,以实现原位黑素瘤的适当切除边缘。六个月后,疤痕上皮炎复发,没有黑色素瘤复发的迹象。据我们所知,文献中尚未报道有梅森现象的黑色素瘤。该病例强调,无论是否存在湿疹,均应在临床和皮肤镜检查基础上评估所有病变。我们的病例增加了另一个可能表现出Meyerson现象的实体,因此,在评估黑素细胞病变时,湿疹的光环不能被视为令人放心的迹象。

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