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首页> 外文期刊>The Australian and New Zealand journal of psychiatry >Neutropenia associated with quetiapine, olanzapine, and aripiprazole.
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Neutropenia associated with quetiapine, olanzapine, and aripiprazole.

机译:中性粒细胞减少症与喹硫平,奥氮平和阿立哌唑有关。

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摘要

Antipsychotics are known to be associated with a risk of neutropenia [1], the best known association being with clozapine. Newer atypical antipsychotics have been developed with the view of being safer alternatives to clozapine. We present the case of a clozapine-naive patient who developed reversible leucopenia (white blood cell (WBC) count <4 X 10~9/L) and neutropenia (neutro-phil count <1.5 X 10~9/L) in response to three different atypical antipsychotic medications. The patient, a Caucasian woman, was first diagnosed with schizophrenia at the age of 50 in 2002. On initial presentation she exhibited bizarre delusions and poor self-care. Exacerbations of psychotic symptoms have led to five further hospital admissions.
机译:已知抗精神病药与中性粒细胞减少症的风险有关[1],最著名的与氯氮平有关。新型非典型抗精神病药已被开发出来,可作为氯氮平的更安全替代品。我们介绍了一位天真的氯氮平患者的情况,该患者在发生以下情况时出现可逆性白细胞减少症(白细胞(WBC)计数<4 X 10〜9 / L)和中性粒细胞减少症(中性粒细胞计数<1.5 X 10〜9 / L)三种不同的非典型抗精神病药物。该患者为高加索女性,于2002年首次诊断为精神分裂症,享年50岁。初诊时,她表现出奇异的妄想和自理能力差。精神病症状的加剧导致五人再次入院。

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