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The July issue: An exegesis

机译:7月号:释经

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Should I read that? Do I need to? And more importantly, do I want to? Readers of this month's Journal have abundant opportunity to pose these very questions. Let us start with a matter firmly tied to clinical practice: do antidepressants help where persons with a dementia also have depression? Macfarlane et al. (2012) dissect the influential study in the UK by Banerjee et al. (201 I) which compared sertraline, mirtazapine and placebo, finding no significant difference. Despite its several flaws, some might conclude that antidepressants are of little use in this group. But it is not so simple: these patients often do get better, but psychosocial treatment needs to be part of the package. Draper (2012) and Snowdon (2012) both endorse the latter unequivocally.
机译:我应该读吗?我需要吗?更重要的是,我要吗?本月刊的读者有很多机会提出这些问题。让我们从与临床实践紧密相关的问题开始:在患有痴呆症的人也患有抑郁症的地方,抗抑郁药是否有帮助? Macfarlane等。 (2012年)剖析了Banerjee等人在英国的影响力研究。 (201 I)比较了舍曲林,米氮平和安慰剂,发现无显着差异。尽管存在一些缺陷,但有些人可能会得出结论,抗抑郁药在这一人群中几乎没有用。但这并不是那么简单:这些患者通常确实会好起来,但是心理社会治疗需要成为其中的一部分。德雷珀(2012)和斯诺登(2012)都明确支持后者。

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