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首页> 外文期刊>The Australian and New Zealand journal of psychiatry >Growth in young adults who screen positive for non-affective psychosis: birth cohort study.
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Growth in young adults who screen positive for non-affective psychosis: birth cohort study.

机译：筛查非情感性精神病呈阳性的年轻人的生长：出生队列研究。

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OBJECTIVE: While birth cohort studies have shown that individuals who develop non-affective psychosis show subtle deviations in cognitive and behavioural developmental trajectories, there is less evidence about deviations in physical growth in these individuals. The purpose of the present study was to examine the association between behaviour and growth and maturation from infancy, through childhood and adolescence to early adulthood and the development of non-affective psychosis in young adults. METHOD: Based on a birth cohort of 3801 young adults, weight and length/height were examined at birth and at years 5, 14 and 21, together with pubertal maturation at year 14. Behavioural measures taken at years 5 and 14 were also examined. Screen-positive non-affective psychosis (SP-NAP) was assessed at year 21 using Composite International Diagnostic Interview, or a self-report checklist. The association between the behavioural and growth measures at birth and at years 5, 14 and 21, and SP-NAP at year 21 was examined using logistic regression. RESULTS: There were 60 subjects in the cohort who were classified as having SP-NAP. In female subjects SP-NAP was significantly associated with being longer with a larger head circumference at birth, and less likely to be associated with being shorter at 21 years, with consistent trend associations for height between. There were no differences for weight. There was no significant association between the variables of interest in male subjects or for the total group. There was also no significant association between pubertal development at age 14 and risk of SP-NAP in either sex. CONCLUSIONS: Unlike developmental behavioural problems, which showed continuity from childhood through adolescence, SP-NAP was not associated with marked deviations in growth trajectory for male subjects, but the present data suggests that female subjects with SP-NAP had an altered skeletal growth trajectory.
机译：目的：尽管出生队列研究表明，患有非情感性精神病的人在认知和行为发展轨迹上存在细微的偏差，但有关这些人身体发育偏差的证据较少。本研究的目的是研究从婴儿期到儿童期，青春期到成年早期的行为与成长和成熟之间的关联，以及年轻人中非情感性精神病的发展。方法：根据3801名年轻成年人的出生队列，对出生时，第5、14和21岁时的体重，身高/身高以及第14岁时的青春期成熟进行了检查。筛查阳性非情感性精神病（SP-NAP）在第21年使用综合国际诊断访谈或自我报告检查表进行评估。使用逻辑回归分析了出生时，第5、14和21岁时的行为和生长指标与第21岁时SP-NAP之间的关联。结果：队列中有60名受试者被归类为SP-NAP。在女性受试者中，SP-NAP与出生时头围较大的时间较长相关，而与21岁时较短的年龄相关的可能性较小，并且两者之间的高度趋势一致。体重没有差异。男性受试者或整个人群的关注变量之间没有显着关联。 14岁时的青春期发育与任何性别的SP-NAP风险之间也没有显着关联。结论：与发育行为问题不同，发育行为问题表现出从童年到青春期的连续性，SP-NAP与男性受试者的生长轨迹没有明显的相关性，但是目前的数据表明，SP-NAP的女性受试者的骨骼生长轨迹发生了变化。

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