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首页> 外文期刊>The Australian and New Zealand journal of psychiatry >Visuospatial working memory deficits and visual pursuit impairments are not directly related in schizophrenia.
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Visuospatial working memory deficits and visual pursuit impairments are not directly related in schizophrenia.

机译:在精神分裂症中,视觉空间工作记忆缺陷和视觉追求障碍不直接相关。

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OBJECTIVE: Patients with schizophrenia show deficits in visuospatial working memory and visual pursuit processes. It is currently unclear, however, whether both impairments are related to a common neuropathological origin. The purpose of the present study was therefore to examine the possible relations between the encoding and the discrimination of dynamic visuospatial stimuli in schizophrenia. METHOD: Sixteen outpatients with schizophrenia and 16 control subjects were asked to encode complex disc displacements presented on a screen. After a delay, participants had to identify the previously presented disc trajectory from a choice of six static linear paths, among which were five incorrect paths. The precision of visual pursuit eye movements during the initial presentation of the dynamic stimulus was assessed. The fixations and scanning time in definite regions of the six paths presented during the discrimination phase were investigated. RESULTS: In comparison with controls, patients showed poorer task performance, reduced pursuit accuracy during incorrect trials and less time scanning the correct stimulus or the incorrect paths approximating its global structure. Patients also spent less time scanning the leftmost portion of the correct path even when making a correct choice. The accuracy of visual pursuit and head movements, however, was not correlated with task performance. CONCLUSIONS: The present study provides direct support for the hypothesis that active integration of visuospatial information within working memory is deficient in schizophrenia. In contrast, a general impairment of oculomotor mechanisms involved in smooth pursuit did not appear to be directly related to lower visuospatial working memory performance in schizophrenia.
机译:目的:精神分裂症患者的视觉空间工作记忆和视觉追踪过程存在缺陷。然而,目前尚不清楚这两种损伤是否与常见的神经病理学起源有关。因此,本研究的目的是检查精神分裂症中动态视觉空间刺激的编码与辨别之间的可能关系。方法:要求16位精神分裂症门诊患者和16位对照对象对屏幕上显示的复杂椎间盘移位进行编码。延迟后,参与者必须从六个静态线性路径(其中五个是不正确的路径)的选择中识别先前显示的光盘轨迹。评估了动态刺激的初始表现过程中视觉追踪眼运动的精度。研究了在辨别阶段出现的六个路径的确定区域中的注视和扫描时间。结果:与对照组相比,患者表现出较差的任务性能,在不正确的试验中追踪准确性下降,并且扫描正确的刺激或接近其整体结构的错误路径的时间更少。即使做出正确的选择,患者也花费更少的时间扫描正确路径的最左侧。但是,视觉追踪和头部运动的准确性与任务绩效无关。结论:本研究为以下观点提供了直接的支持:在工作记忆中视觉空间信息的主动整合缺乏精神分裂症。相比之下,精神分裂症中顺滑追赶的动眼机制的一般损害似乎与较低的视觉空间工作记忆表现没有直接关系。

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