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首页> 外文期刊>The Australian and New Zealand journal of psychiatry >Early intervention for adolescents with borderline personality disorder: quasi-experimental comparison with treatment as usual.
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Early intervention for adolescents with borderline personality disorder: quasi-experimental comparison with treatment as usual.

机译:边缘性人格障碍青少年的早期干预:与往常一样的准实验比较。

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OBJECTIVE: The aim of the present study was to compare the effectiveness of specialized team-based early intervention for borderline personality disorder (BPD) with treatment as usual. METHOD: In a quasi-experimental design, 32 outpatients who received historical treatment as usual (H-TAU) were compared with 78 participants from a recently published randomized controlled trial of cognitive analytic therapy (CAT; n = 41) versus manualized good clinical care (GCC; n = 37), conducted in a specialized early intervention service for BPD (the Helping Young People Early (HYPE) programme). All participants were 15-18-year-old outpatients who fulfilled 2-9 DSM-IV BPD criteria. It was predicted that, compared with H-TAU, HYPE + GCC and HYPE + CAT would show greater reductions in psychopathology and parasuicidal behaviour and greater improvement in global functioning over 24 months. RESULTS: At 24 month follow up: (i) HYPE + CAT had lower standardized levels of, and a significantly faster standardized rate of improvement in, internalizing and externalizing psychopathology, compared with H-TAU; and (ii) HYPE + GCC had lower standardized levels of internalizing psychopathology and a faster rate of improvement in global functioning than H-TAU. HYPE + CAT yielded the greatest median improvement on the four continuous outcome measures over 24 months. No adverse effects were shown with any of the treatments. CONCLUSIONS: Specialized early intervention for subsyndromal or full-syndrome BPD is more effective than TAU, with HYPE + CAT being the most effective intervention. Reform of existing services using the HYPE model might yield substantial improvements in patient outcomes.
机译:目的:本研究的目的是比较常规的基于团队的专业性边缘性人格障碍(BPD)早期干预的疗效。方法:在准实验设计中,将32例接受常规治疗的门诊患者(H-TAU)与最近发表的认知分析治疗随机对照试验(CAT; n = 41)与手动良好临床护理的78名参与者进行了比较(GCC; n = 37),是针对BPD(早期帮助年轻人(HYPE)计划)的专门早期干预服务进行的。所有参与者均为15-18岁的门诊患者,符合2-9 DSM-IV BPD标准。据预测,与H-TAU相比,HYPE + GCC和HYPE + CAT在24个月内将表现出更大的精神病理学和自杀性行为减少以及整体功能改善。结果:在24个月的随访中:(i)与H-TAU相比,HYPE + CAT的心理病理学,内在化和外在化的标准化水平较低,并且标准化的改善速度明显更快; (ii)与H-TAU相比,HYPE + GCC的内化心理病理学标准化水平较低,整体功能改善速度更快。在过去的24个月中,HYPE + CAT在四个连续结果测量中的中位数改善最大。任何治疗均未显示不良反应。结论:针对亚综合征或全综合征BPD的专门早期干预比TAU更有效,HYPE + CAT是最有效的干预措施。使用HYPE模型对现有服务进行改革可能会大大改善患者的预后。

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