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Anti-TNF alpha therapies in the treatment of Crohn's disease

机译:抗TNFα治疗克罗恩氏病

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摘要

THE incidence of Crohn's disease in Australia is increasing though the incidence of ulcerative colitis is steady. There may have been a three-fold increase in the past three decades with Crohn's disease and it is estimated that 30,000 Australians suffer from this problem. The same pattern of inflammatory bowel disease is also current within the paediatric community, so it is likely that there will be a continuing increase in Crohn's disease in the future. While the incidence of Crohn's disease is similar in males and females, the disease can start at any age and commonly occurs in those aged between 15 and 30 years. It is, however, increasingly commonly recognised within the paediatric population. There are genetic, racial and cultural factors that may influence susceptibility to this disease.
机译:尽管溃疡性结肠炎的发病率稳定,但澳大利亚的克罗恩病发病率正在增加。在过去的三十年中,克罗恩氏病的发病率可能增长了三倍,估计有30,000澳洲人患有此病。小儿社区目前也存在着相同的炎症性肠病模式,因此将来克罗恩病有可能继续增加。尽管克罗恩氏病的发病率在男性和女性中相似,但该病可以在任何年龄开始,通常发生在15至30岁之间。然而,它在儿科人群中越来越普遍地被认可。有遗传,种族和文化因素可能会影响该疾病的易感性。

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