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首页> 外文期刊>The Australian Journal of Pharmacy >Folic acid and vitamins B6 and B12 do not reduce the risk of major cardiovascular events
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Folic acid and vitamins B6 and B12 do not reduce the risk of major cardiovascular events

机译：叶酸和维生素B6和B12不会降低发生重大心血管事件的风险

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摘要

DURING the past few years, elevated blood levels of homocysteine (a sulfur-containing amino acid) have been linked to increased risk of premature coronary artery disease, stroke, and thromboembolism (venous blood clots), even among people who have normal cholesterol levels. Elevated homocysteine levels appear to contribute to atherosclerosis in at least three ways: a direct toxic effect that damages the cells lining the inside of the arteries; interference with clotting factors; and oxidation of low-density lipoproteins (LDL). As would be expected, it has been observed in a number of studies that lower homocysteine levels are associated with lower rates of coronary heart disease and stroke.
机译：在过去的几年中，即使是胆固醇水平正常的人，高半胱氨酸（一种含硫的氨基酸）的血药浓度升高也与早发冠状动脉疾病，中风和血栓栓塞（静脉血栓）的风险增加有关。高半胱氨酸水平的升高似乎至少以三种方式导致了动脉粥样硬化：直接的毒性作用，损害了动脉内壁的细胞;干扰凝血因子;和低密度脂蛋白（LDL）的氧化。可以预期，在许多研究中发现，同型半胱氨酸水平降低与冠心病和中风发生率降低有关。

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