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首页> 外文期刊>The Australian Journal of Pharmacy >Combination of paracetamol and ibuprofen effective for treating fever in infants and young children
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Combination of paracetamol and ibuprofen effective for treating fever in infants and young children

机译：对乙酰氨基酚与布洛芬合用可有效治疗婴幼儿发烧

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摘要

FEVER is one of the most common presenting signs of illness in infants and young children They are particularly susceptible to fever because of their small body size, high ratio of body surface area to weight, and low amount of subcutaneous fat.Although most experts consider fever a beneficial physiologic response to the infectious process, it can lead to patient irritability and stress as well as high parental anxiety. Parents usually wish to use an antipyretic agent.Paracetamol and ibuprofen are widely used.Paracetamol is absorbed in the gastrointestinal tract, reaching peak plasma concentrations within 30 minutes. The time to maximal temperature reduction is approximately two hours. The recommended dose of paracetamol is 12 to 15mg/kg every six hours.
机译：发烧是婴幼儿最常见的疾病征兆之一，由于其体型小，体表面积与体重的比率高以及皮下脂肪含量低，它们特别容易发烧，尽管大多数专家都认为发烧对传染过程有益的生理反应，会导致患者烦躁不安和压力以及父母的高度焦虑。父母通常希望使用退热药，对乙酰氨基酚和布洛芬被广泛使用，对乙酰氨基酚在胃肠道中被吸收，在30分钟内达到峰值血浆浓度。达到最大降温时间大约为两个小时。对乙酰氨基酚的推荐剂量为每6小时12至15mg / kg。

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