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The Effect of Bovine Respiratory Syncytial Virus Vaccination on Health, Feedlot Performance and Carcass Characteristics of Feeder Cattle

机译:牛呼吸道合胞病毒疫苗接种对饲养牛的健康,饲养场性能和cas体特性的影响

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A two-year study was conducted to determine the effects of a feedlot-arrival modified-live viral vaccination protocol containing adjuvanted bovine respiratory syncytial virus (BRSV) compared to a vaccination protocol not including adjuvanted BRSV on health, feedlot performance and carcass characteristics of feeder cattle. The vaccine products compared were a multivalent adjuvanted modified-live bovine rhinotracheitis, virus diarrhea, parainfluenza-3, respiratory syncytial virus vaccine (4-WAY) and amultivalent adjuvanted vaccine of similar formulation which did not contain BRSV (3-WAY). Atotal of 50 blocks, evenly divided between steers and heifers, were allocated to the study involving 19,099 cattle. Yearling feeder cattle were primarily used, with 161 average days on feed. Interactions were not observed between vaccine treatment and feedlot location, placement season, animal sex or animal age. Percent of overall morbidity due to respiratory disease was less (P = 0.0629) for cattle vaccinated with 4-WAY vaccine compared to 3-WAY Overall mortality, expressed as the number of animals per pen that died (P = 0.0020) and percent deaths per pen (P = 0.0007), was improved for cattle vaccinated with 4-WAY versus 3-WAY vaccine. The number of animals perpen that died due to respiratory disease was less (P = 0.0060) for 4-WAY compared to 3-WAY. Overall case fatality, expressed as the number of treated animals per pen that died (P = 0.0116) and percent of treated animals that died (P = 0.1027), was improved for cattle vaccinated with 4-WAY versus 3-WAY vaccine. The number of animals treated for respiratory disease per pen that died was less (P = 0.0132) in the 4-WAY group compared to 3-WAY. Medical treatment cost per animal treated was 2.01 dollar per head less (P = 0.0688) for cattle vaccinated with 4-WAY. All other health parameters measured were similar between the two vaccine treatments. Feedlot performance variables such as dry matter feed intake, average daily gain and feed conversion were not different between the two vaccine treatments. The majority of carcass characteristics measured were similar for the two vaccine treatments; however, the percent Yield Grade 2 carcasses were less (P = 0.0501) and the percent Yield Grade 3 carcasses greater (P = 0.0561) for cattle vaccinated with 4-WAY compared to 3-WAY. Net feedlot margin was numerically increased 4.33 dollar per head for cattle vaccinated with 4-WAY vaccine, but this difference was not statistically different (P = 0.3057). It appears fromthis study that feedlot health parameters and some production costs can be improved for feeder cattle immunized for BRSV with an adjuvanted modified live antigen.
机译:进行了一项为期两年的研究,以确定含有佐剂牛呼吸道合胞病毒(BRSV)的饲养场到来的改良活病毒疫苗接种方案与不包括佐剂BRSV的疫苗接种方案相比对健康,饲养场性能和饲养者car体特性的影响牛。比较的疫苗产品是多价佐剂改良活牛鼻气管炎,病毒性腹泻,副流感-3,呼吸道合胞病毒疫苗(4-WAY)和类似配方的多价佐剂疫苗,不含BRSV(3-WAY)。研究共分配了50个街区,平均分为ste牛和小母牛,涉及19,099头牛。主要使用一岁饲养牛,平均饲养日数为161天。在疫苗处理和饲养场位置,放置季节,动物性别或动物年龄之间未观察到相互作用。与3-WAY总体死亡率相比,接种4-WAY疫苗的牛由于呼吸道疾病而导致的总体发病率较低(P = 0.0629),表示为每只死的动物数(P = 0.0020)和每只动物的死亡率相对于3-WAY疫苗接种的牛,改进了围栏(P = 0.0007)。与3-WAY相比,4-WAY因呼吸道疾病致死的动物数量较少(P = 0.0060)。相对于3-WAY疫苗接种的牛,总的病死率得到了改善,表示为每只笔死亡的治疗的动物数(P = 0.0116)和死亡的治疗的动物百分数(P = 0.1027)。与3-WAY组相比,4-WAY组每只因呼吸道疾病死亡的动物死亡的动物数量较少(P = 0.0132)。每头动物接种4-WAY疫苗后的牛的医疗费用每头少了2.01美元(P = 0.0688)。两种疫苗治疗之间测得的所有其他健康参数相似。两种疫苗处理之间的饲养场性能变量(如干物质采食量,平均日增重和饲料转化率)没有差异。两种疫苗处理方法测得的大多数car体特征相似。然而,与3-WAY相比,接种4-WAY的牛的2级car体的百分率更低(P = 0.0501),而采用3WAY的三级greater体的百分数更高(P = 0.0561)。用4-WAY疫苗接种的牛的净饲养场利润每头增加了4.33美元,但这一差异没有统计学差异(P = 0.3057)。从这项研究看来,用佐剂修饰的活抗原免疫BRSV的饲养牛可以改善饲养场的健康参数和一些生产成本。

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