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Therapeutic processes and clinical outcomes of body psychotherapy in chronic schizophrenia - An open clinical trial

机译:身体心理治疗在慢性精神分裂症中的治疗过程和临床结果-一项开放的临床试验

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Persistent negative symptoms are an ongoing challenge in the treatment of chronic schizophrenia. Evidence from randomised controlled trials suggests that artson-verbal therapies may be effective in treating negative symptoms of schizophrenia. These treatments have not yet been evaluated in open clinical settings.The present uncontrolled clinical trial examines the therapeutic processes and clinical outcomes of group body psychotherapy (BPT) on marked negative symptoms in patients with chronic schizophrenia. Changes in symptom scores, subjective quality of life, social functioning and emotional processing between baseline and post-treatment were assessed. The ratings from clinical assessments of independent researchers were compared with the post-therapy summary assessment of the therapists.A total of 39 eligible patients were referred, out of which 18 patients agreed to participate and received BPT in addition to treatment as usual within three therapy groups run by different therapists. Patients had high symptom levels and low psychosocial functioning at baseline. Negative symptoms and general psychopathology significantly reduced during treatment. Positive symptoms and other outcomes did not change. Researcher ratings of psychopathology were in line with the assessment of clinical outcome by therapists and qualitative observations on changes in movement behaviour during therapy.The results of this study are consistent with findings from a RCT (Rohricht & Priebe, 2006), indicating that BPT is associated with reduced negative symptoms even when administered in routine clinical settings. Therapists' qualitative judgements may be considered as a valid source for assessing treatment outcomes. Future studies should explore effects of longer term treatments on other outcomes.
机译:在慢性精神分裂症的治疗中,持续的阴性症状是一个持续的挑战。随机对照试验的证据表明,艺术/非语言疗法可能有效治疗精神分裂症的阴性症状。这些治疗尚未在开放的临床环境中进行评估。本项不受控制的临床试验检查了团体精神心理治疗(BPT)对慢性精神分裂症患者明显阴性症状的治疗过程和临床结果。评估基线和治疗后症状评分,主观生活质量,社会功能和情绪加工的变化。将独立研究人员的临床评估评分与治疗师的治疗后总结评估进行比较,总共转诊了39例合格患者,其中18例患者同意参加并接受了BPT的三种治疗方法以及常规治疗小组由不同的治疗师经营。患者在基线时症状较高,社会心理功能较低。在治疗期间,阴性症状和一般的精神病理学显着降低。阳性症状和其他结局没有改变。研究人员对心理病理学的评分与治疗师对临床结局的评估以及对治疗过程中运动行为变化的定性观察相吻合。本研究的结果与RCT的发现一致(Rohricht&Priebe,2006),表明BPT是即使在常规临床环境中使用,也可减少不良症状。治疗师的定性判断可以被视为评估治疗结果的有效依据。未来的研究应探讨长期治疗对其他结局的影响。

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