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Emotional memory in bipolar disorder.

机译:双相情感障碍的情绪记忆。

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BACKGROUND: Cognitive impairment has been well documented in bipolar disorder. However, specific aspects of cognition such as emotional memory have not been examined. AIMS: To investigate episodic emotional memory in bipolar disorder, as indicated by performance on an amygdala-related cognitive task. METHOD: Twenty euthymic patients with bipolar disorder and 20 matched controls were recruited. Participants were shown a slide show of an emotionally neutral story, or a closely matched emotionally arousing story. One week later, participants were assessed on a memory-recall test. RESULTS: In contrast with the pattern observed in controls, patients with bipolar disorder had no enhancement of memory for the emotional content of the story (F=14.7, d.f.=1,36, P0.001). The subjective perception of the emotional impact of the emotional condition was significantly different from that of the neutral condition in controls but not in people with bipolar disorder. CONCLUSIONS: Our data suggest that the physiological pattern of enhanced memory retrieval for emotionally bound information is blunted in bipolar disorder.
机译:背景:认知障碍已在双相情感障碍中得到了充分的证明。但是,尚未检查认知的特定方面,例如情绪记忆。目的:研究双相情感障碍的情境性情感记忆,如杏仁核相关认知任务的表现所表明的。方法:招募了20名患有躁郁症的正常人和20名匹配的对照。向参与者展示了一个情绪中立的故事的幻灯片,或一个与情绪激动的故事紧密匹配的故事。一周后,参加者接受了回忆记忆测试。结果:与对照组相比,躁郁症患者对故事的情感内容的记忆力没有增强(F = 14.7,d.f。= 1,36,P <0.001)。在对照中,对情绪状态的情感影响的主观感知与中性状况的主观感知显着不同,但在躁郁症患者中则没有。结论:我们的数据表明,在双相情感障碍中,增强的用于情感约束信息的记忆检索的生理学模式减弱。

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