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首页> 外文期刊>The British journal of psychiatry : >Psychotherapy plus antidepressant for panic disorder with or without agoraphobia: systematic review.
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Psychotherapy plus antidepressant for panic disorder with or without agoraphobia: systematic review.

机译：心理疗法加抗抑郁药治疗恐慌症（不论是否患有广场恐惧症）：系统评价。

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摘要

BACKGROUND: Panic disorder can be treated with psychotherapy, pharmacotherapy or a combination of both. AIMS: To summarise the evidence concerning the short- and long-term benefits and adverse effects of a combination of psychotherapy and antidepressant treatment. METHOD: Meta-analyses and meta-regressions were undertaken using data from all relevant randomised controlled trials identified by a comprehensive literature search. The primary outcome was relative risk (RR) of response. RESULTS: We identified 23 randomised comparisons (21 trials involving a total of 1709 patients). In the acute-phase treatment, the combined therapy was superior to antidepressant pharmacotherapy (RR=1.24,95% CI1.02-1.52) or psychotherapy (RR=1.16,95% CI1.03-1.30). After termination of the acute-phase treatment, the combined therapy was more effective than pharmacotherapy alone (RR=1.61,95% CI1.23-2.11) and was as effective as psychotherapy (RR=0.96, 95% CI 0.79-1.16). CONCLUSIONS: Either combined therapy or psychotherapy alone may be chosen as first-line treatment for panic disorder with or without agoraphobia, depending on the patient's preferences.
机译：背景：恐慌症可以通过心理治疗，药物治疗或两者结合治疗。目的：总结有关心理治疗和抗抑郁治疗相结合的短期和长期益处以及不良反应的证据。方法：荟萃分析和荟萃分析使用了来自所有相关随机对照试验的数据，这些数据通过全面的文献检索确定。主要结果是反应的相对风险（RR）。结果：我们确定了23项随机比较（21项试验，共1709名患者）。在急性期治疗中，联合疗法优于抗抑郁药物疗法（RR = 1.24,95％CI1.02-1.52）或心理疗法（RR = 1.16.95％CI1.03-1.30）。急性期治疗终止后，联合治疗比单独药物治疗更有效（RR = 1.61,95％CI1.23-2.11），并且与心理治疗一样有效（RR = 0.96，95％CI 0.79-1.16）。结论：根据患者的喜好，单独的综合治疗或心理治疗可以被选为伴或不伴恐慌症的恐慌症的一线治疗方法。

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