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首页> 外文期刊>The British journal of psychiatry : >Longitudinal investigation into childhood- and adolescence-onset depression: psychiatric outcome in early adulthood.
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Longitudinal investigation into childhood- and adolescence-onset depression: psychiatric outcome in early adulthood.

机译：对儿童期和青少年期抑郁症的纵向调查：成年初期的精神病学预后。

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BACKGROUND: Major depression in childhood or adolescence increases the risk off affective disorder in adulthood. The precise nature and course of the subsequent disorder remain unclear. AIMS: To investigate long-term psychiatric outcome of school-age depression in community and clinic samples. METHOD: A group of 113 young adults were followed up after a mean of 7.8 years (s.e.=15). RESULTS: Groups with persistent and recurrent depression were identified. Recurrence of affective disorder was similar in clinic and community groups. The clinic group had significantly longer index episodes; these were predicted by an early psychiatric history, longer episode duration before treatment and greater impairment. Being female, having higher self-report depression scores and comorbidity at index episode predicted earlier recurrence. Males were more likely to have persistent depression. CONCLUSIONS: Prognosis is similar in young people with depression from community and clinical samples. Boys from a clinical sample are at higher risk than girls of becoming persistently and severely mentally ill.
机译：背景：儿童期或青少年期的严重抑郁症增加了成人情感障碍的风险。随后疾病的确切性质和病程尚不清楚。目的：在社区和临床样本中调查学龄期抑郁症的长期精神病学结果。方法：一组平均年龄为7.8年（s.e. = 15）的113名年轻成年人进行了随访。结果：确定了患有持续性和复发性抑郁的人群。在临床和社区人群中，情感障碍的复发率相似。临床组的指数发作时间明显更长;这些是通过早期精神病史，治疗前发作持续时间较长和损伤更大而预测的。作为女性，自我报告的抑郁评分较高和指数发作时合并症预示着较早的复发。男性更有可能持续患有抑郁症。结论：社区和临床样本的年轻人抑郁的预后相似。来自临床样本的男孩患持久性和严重精神疾病的风险高于女孩。

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