As members of the recent National Institute for Health and Care Excellence (NICE) clinical guideline update for schizophrenia1 (M.B. and D.S.), we read with interest the excellent meta-analysis of CBT for symptoms of schizophrenia by Jauhar et al.2 The results are broadly in line with the NICE review and particularly that of Wykes et al,3 which showed that studies with high methodological rigour, including masking, have a small effect size for positive and total symptoms. Clearly cognitive-behavioural therapy (CBT) is no panacea; but neither is it ineffective. Meta-analyses bring together all trials, with patients drawn from heterogeneous populations, including different phases of illness.
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