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首页> 外文期刊>The European Journal of Neuroscience >Differential activation of hippocampus and amygdala following spatial learning under stress.
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Differential activation of hippocampus and amygdala following spatial learning under stress.

机译：在压力下进行空间学习后海马和杏仁核的差异激活。

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摘要

We examined the activation of memory-related processes in the hippocampus and the amygdala following spatial learning under stress, in the rat. Animals were trained in a water maze in a massed spatial task under two stress conditions (cold and warm water). In the dorsal CA1, training was accompanied by increased phosphorylation of ERK2 only in animals that have acquired the task (irrespective of whether they were trained in cold or warm water). In the amygdala, significant activation of ERK2 was found only in animals that learned the task well under high levels of stress. Hence, the results suggest that the amygdala and the hippocampus are differentially activated following spatial learning, depending on the level of stress involved.
机译：我们研究了大鼠在压力下的空间学习后海马和杏仁核中记忆相关过程的激活。在两个压力条件（冷水和温水）下，在大型空间任务中的水迷宫中对动物进行训练。在背侧CA1中，仅在完成任务的动物中进行训练，伴随着ERK2磷酸化的增加（无论它们是在冷水中还是在温水中进行训练）。在杏仁核中，只有在高压力下能很好地学习这项任务的动物中才能发现ERK2的显着激活。因此，结果表明，空间学习后杏仁核和海马体被不同程度地激活，这取决于所涉及的压力水平。

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