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首页> 外文期刊>The European Journal of Neuroscience >Concurrent TMS-fMRI reveals dynamic interhemispheric influences of the right parietal cortex during exogenously cued visuospatial attention.
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Concurrent TMS-fMRI reveals dynamic interhemispheric influences of the right parietal cortex during exogenously cued visuospatial attention.

机译：并发TMS-fMRI揭示了在外源性提示视觉空间注意过程中右顶叶皮层的动态半球影响。

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We used concurrent transcranial magnetic stimulation and functional MRI (TMS-fMRI) during a visuospatial cueing paradigm in humans, to study the causal role of the right angular gyrus (AG) as a source of attentional control. Our findings show that TMS over the right AG (high vs. low intensity) modulates neural responses interhemispherically, in a manner that varies dynamically with the current attentional condition. The behavioural impact of such TMS depended not only on the target hemifield but also on exogenous cue validity, facilitating spatial reorienting to invalidly cued right visual targets. On a neural level, right AG TMS had corresponding interhemispheric effects in the left AG and left retinotopic cortex, including area V1. We conclude that the direction of covert visuospatial attention can involve dynamic interplay between the right AG and remote interconnected regions of the opposite left hemisphere, whereas our findings also suggest that the right AG can influence responses in the retinotopic visual cortex.
机译：我们在人的视觉空间提示范式中使用了并发的经颅磁刺激和功能性MRI（TMS-fMRI），以研究直角回（AG）作为注意控制源的因果作用。我们的研究结果表明，正确的AG上的TMS（高强度与低强度）会在半球间调节神经反应，其方式会随当前注意力状况而动态变化。这种TMS的行为影响不仅取决于目标半场，而且还取决于外在提示的有效性，从而有利于空间重新定向到无效提示的右视觉目标。在神经水平上，右AG TMS对左AG和左视网膜原位皮层（包括V1区）具有相应的半球效应。我们得出结论，隐蔽视觉空间注意力的方向可能涉及右AG和相对的左半球的远程互连区域之间的动态相互作用，而我们的发现也表明右AG可以影响视网膜视听皮层的反应。

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