...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The European Journal of Neuroscience >Peripheral auditory asymmetry in infantile autism.
【24h】

Peripheral auditory asymmetry in infantile autism.

机译：婴儿自闭症的周围听觉不对称。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Difficulty in filtering relevant auditory information in background noise is one of the features of autism. Auditory filtering processes can be investigated at the peripheral level as they are hypothesized to involve active cochlear mechanisms which are regulated by the efferent activity of the medial olivocochlear (MOC) system. The aim of the present work was therefore to assess these peripheral auditory processes in 22 children and adolescents with autism compared with age- and gender-matched normal controls. Active cochlear mechanisms were evaluated with transiently evoked otoacoustic emissions (TEOAEs) and MOC system efficiency was assessed via TEOAEs which are decreased when stimulating the contralateral ear with noise. The MOC system evaluation was performed on 18 of the 22 children. In both studies, results were analysed according to age (from 4 to 10 years and from 11 to 20 years). The main result concerns the asymmetry of the efferent system which differs in individuals with autism. Several neural processes might be hypothesized as involved in the results obtained as the MOC system which originates in the brainstem received regulating controls from upper brain structures including auditory cortex. Lateralization abnormalities at the auditory periphery may reflect indirectly a problem at a higher level of auditory processing. A second important result shows a decrease in TEOAE amplitude with age, in patients, that may correspond to a decrease in hearing sensitivity.
机译：背景噪声中难以过滤相关的听觉信息是自闭症的特征之一。听觉过滤过程可以在外围水平进行研究，因为它们被假定为涉及主动的耳蜗机制，该机制由内侧少脂（MOC）系统的传出活动来调节。因此，本研究的目的是评估与年龄和性别相匹配的正常对照相比，在22名自闭症儿童和青少年中的这些外周听觉过程。通过短暂诱发的耳声发射（TEOAE）评估主动耳蜗机制，并通过TEOAE评估MOC系统效率，当用噪声刺激对侧耳朵时会降低。对22名儿童中的18名进行了MOC系统评估。两项研究均根据年龄（4至10岁和11至20岁）分析结果。主要结果与传出系统的不对称性有关，该系统在自闭症患者中有所不同。可能假设有几种神经过程参与了获得的结果，因为起源于脑干的MOC系统受到包括听觉皮层在内的上层大脑结构的调节控制。听觉外围的横向异常可能间接反映出较高水平的听觉处理问题。第二个重要结果表明，患者的TEOAE振幅随年龄的降低而降低，这可能与听力敏感性降低有关。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号