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首页> 外文期刊>The European Journal of Neuroscience >Brain temperature fluctuation: a reflection of functional neural activation.
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Brain temperature fluctuation: a reflection of functional neural activation.

机译:脑温波动:功能性神经激活的反映。

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摘要

Although it is known that relatively large increases in local brain temperature can occur during behaviour and in response to various novel, stressful and emotionally arousing environmental stimuli, the source of this heat is not clearly established. To clarify this issue, we monitored the temperature in three brain structures (dorsal and ventral striatum, cerebellum) and in arterial blood at the level of the abdominal aorta in freely moving rats exposed to several environmental challenges ranging from traditional stressors to simple sensory stimuli (cage change, tail pinch, exposure to another male rat, a female rat, a mouse or an unexpected sound). We found that brain temperature was consistently higher than arterial blood temperature, and that brain temperature increased prior to, and to a greater extent than, the increase in blood temperature evoked by each test challenge. Thus, the local metabolic consequences of widely correlated neural activity appear to be the primary source of increases in brain temperature and a driving force behind the associated changes in body temperature.
机译:尽管已知在行为过程中以及响应各种新颖的,压力性的和情绪激动性的环境刺激会导致局部脑部温度相对较大的升高,但这种热量的来源尚未明确。为了澄清这个问题,我们在自由移动的老鼠中暴露了从传统压力源到简单的感觉刺激(包括简单的感觉刺激)暴露的几种环境挑战,监测了三个大脑结构(背侧和腹侧纹状体,小脑)以及腹主动脉水平动脉血的温度更换笼子,捏尾巴,暴露于另一只雄性大鼠,雌性大鼠,小鼠或意外声音)。我们发现,脑温度始终高于动脉血液温度,并且脑温度在每次测试激发所引起的血压升高之前(在更大程度上)升高。因此,广泛相关的神经活动的局部代谢后果似乎是脑温升高和体温相关变化背后的驱动力。

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