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首页> 外文期刊>The European Journal of Neuroscience >Expression of CRABP I mRNA in fastigial cells of the developing cerebellum.
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Expression of CRABP I mRNA in fastigial cells of the developing cerebellum.

机译:CRABP I mRNA在发育中的小脑的小脑细胞中的表达。

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摘要

The expression of the cellular retinoic acid binding protein type I (CRABP I) was examined in the early phase of cerebellar development in the mouse. The CRABP I was expressed from embryonic day (E) 10.5 to E15.5 in the cerebellar plate. The expression was diffused at E10.5-E11.5 and thereafter localized in a small rostrodorsal area of the cerebellar territory of both sides. By using in situ hybridization and both immunohistochemistry and carbocyanine tracing procedures, we identified the fastigial cells as the population that expresses CRABP I in the cerebellum. The results suggest that these cells play a critical role in the early development of the cerebellum.
机译:在小鼠小脑发育的早期检查了细胞维甲酸结合蛋白I型(CRABP I)的表达。 CRABP I在小脑板的胚胎天(E)10.5至E15.5表达。该表达在E10.5-E11.5处扩散,此后定位在两侧小脑区域的小轮状嗅觉区域。通过使用原位杂交,免疫组织化学和碳花青示踪程序,我们确定了小脑上皮细胞为在小脑中表达CRABP I的群体。结果表明这些细胞在小脑的早期发育中起关键作用。

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