• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The European Journal of Neuroscience >Amygdala norepinephrine levels after training predict inhibitory avoidance retention performance in rats.
【24h】

Amygdala norepinephrine levels after training predict inhibitory avoidance retention performance in rats.

机译：训练后杏仁核去甲肾上腺素水平预测大鼠抑制回避保留表现。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Previous findings indicate that footshock and several drugs that modulate memory consolidation alter norepinephrine (noradrenaline) release in the amygdala, as assessed by in vivo microdialysis and high-performance liquid chromatography. Such findings suggest that norepinephrine release in the amygdala may be critical for regulating memory consolidation. The present study was the first to examine the relationship between norepinephrine release in the amygdala assessed after inhibitory avoidance training and 24-h retention performance within individual animals. Norepinephrine levels increased to > 300% of pretraining baseline 30 min after training and remained elevated for 2 h. In individual rats, the increase in norepinephrine levels after training correlated highly with 24-h retention performance. These findings indicate that the degree of activation of the noradrenergic system within the amygdala in response to a novel, emotionally arousing experience predicts the extent of long-term memory for that experience.
机译：先前的发现表明，通过体内微透析和高效液相色谱评估，足底震颤和几种调节记忆巩固的药物会改变杏仁核中去甲肾上腺素（去甲肾上腺素）的释放。这些发现表明杏仁核中去甲肾上腺素的释放对于调节记忆巩固可能至关重要。本研究是第一个研究抑制回避训练后杏仁核中去甲肾上腺素释放与动物体内24小时保留表现之间关系的研究。训练后30分钟，去甲肾上腺素水平增加到训练前基线的300％以上，并持续2 h。在个别大鼠中，训练后去甲肾上腺素水平的增加与24小时保留表现高度相关。这些发现表明杏仁核内去甲肾上腺素能系统对一种新颖的，引起情绪激动的经历的激活程度预示了对该经历的长期记忆的程度。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号