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首页> 外文期刊>The European Journal of Neuroscience >The neural substrate of orientation short-term memory and resistance to distractor items.
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The neural substrate of orientation short-term memory and resistance to distractor items.

机译：定向短期记忆和对干扰物抵抗的神经底物。

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摘要

We used Positron Emission Tomography to map the neural substrate of human short-term memory for orientation, defined as retaining a single orientation in memory over a long delay, by comparing a successive discrimination task with a 6-s delay to the same task with a brief 0.3 s delay and to an identification control task. Short-term memory engaged the superior parietal lobe bilaterally, the middle occipital gyrus bilaterally and the left dorsolateral prefrontal cortex. In addition, we studied the resistance to a distractor item by comparing the successive discrimination task with long delay, with and without an intervening distractor stimulus. This manipulative process engaged left ventral premotor cortex and left dorsolateral prefrontal cortex. The activation of left dorsolateral prefrontal cortex is interpreted as reflecting co-ordination between task components. These results, combined with those of two previous studies using an identical reduction strategy, underscore the functional heterogeneity in the prefrontal cortex during short-term and working memory.
机译：我们使用正电子发射断层扫描来映射人类短期记忆的神经基质的方向，即通过将具有6 s延迟的连续判别任务与具有短暂的0.3 s延迟并执行识别控制任务。短期记忆双侧参与顶壁上叶，双侧枕中回和左背外侧前额叶皮层。此外，我们通过比较具有较长延迟和不存在干扰物刺激的连续歧视任务来研究对干扰物的抵抗力。该操纵过程涉及左腹前运动皮层和左后外侧前额叶皮层。左背外侧前额叶皮层的激活被解释为反映任务组件之间的协调。这些结果，与之前使用相同的减少策略进行的两项研究相结合，强调了短期和工作记忆中前额叶皮层的功能异质性。

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