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首页> 外文期刊>The European Journal of Neuroscience >Impact of aging brain circuits on cognition
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Impact of aging brain circuits on cognition

机译：脑回路衰老对认知的影响

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Brain networks that engage the hippocampus and prefrontal cortex are central for enabling effective interactions with our environment. Some of the cognitive processes that these structures mediate, such as encoding and retrieving episodic experience, wayfinding, working memory and attention are known to be altered across the lifespan. As illustrated by examples given below, there is remarkable consistency across species in the pattern of age-related neural and cognitive change observed in healthy humans and other animals. These include changes in cognitive operations that are known to be dependent on the hippocampus, as well as those requiring intact prefrontal cortical circuits. Certain cognitive constructs that reflect the function of these areas lend themselves to investigation across species, allowing brain mechanisms at different levels of analysis to be studied in greater depth.
机译：参与海马和前额叶皮层的大脑网络对于实现与环境的有效交互至关重要。这些结构所介导的一些认知过程，例如编码和检索的情景经历，寻路，工作记忆和注意力，在整个生命周期中都会发生变化。如以下示例所示，在健康人类和其他动物中观察到的与年龄相关的神经和认知变化模式中，各物种之间具有显着的一致性。这些包括已知依赖于海马体的认知操作的变化，以及需要完整的前额叶皮层回路的变化。反映这些区域功能的某些认知构造适合跨物种研究，从而可以更深入地研究不同分析级别的大脑机制。

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