...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The European Journal of Neuroscience >Visual presentation of novel objects and new spatial arrangements of objects differentially activates the medial temporal lobe subareas in humans.
【24h】

Visual presentation of novel objects and new spatial arrangements of objects differentially activates the medial temporal lobe subareas in humans.

机译：新颖物体的视觉呈现和物体的新空间排列差异性地激活了人类的颞叶内侧区域。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Abstract A number of studies in rodents and monkeys report a distinction between the contributions of the hippocampus and perirhinal cortex to memory, such that the hippocampus is crucial for spatial memory whereas the perirhinal cortex has a pivotal role in perception and memory for visual objects. To determine if there is such a distinction in humans, we conducted a functional magnetic resonance imaging study to compare the medial temporal lobe responses to changes in object identity and spatial configurations of objects. We found evidence for the predicted distinction between hippocampal and perirhinal cortical activations, although part of the hippocampus was also activated by identification of novel objects. Additionally, an anterior-posterior activation gradient emerged inside the hippocampus and parahippocampal cortex. The anterior hippocampus, perirhinal cortex and anterior parahippocampal cortex are involved in perception of contextually novel objects, whereas the posterior hippocampus and posterior parahippocampal cortex are involved in processing of novel arrangements of familiar objects. These results demonstrate that there is a functional dissociation between processing of novel object identities and new spatial locations of objects among the subregions of medial temporal lobe structures in humans also.
机译：摘要啮齿动物和猴子的许多研究报告都将海马和周围神经皮质对记忆的贡献区分开来，因此海马对空间记忆至关重要，而周围神经皮质在视觉对象的感知和记忆中起着关键作用。为了确定人类是否存在这种区别，我们进行了功能磁共振成像研究，以比较内侧颞叶对物体身份和物体空间配置变化的反应。我们发现了预测的海马和周围神经皮层激活之间的区别的证据，尽管海马的一部分也通过识别新物体而被激活。另外，海马和海马旁皮质内部出现了前后激活梯度。前海马，周围神经皮层和前海马旁皮质参与上下文新颖对象的感知，而后海马和后海马旁皮质参与熟悉对象的新颖安排的处理。这些结果表明，在人类的内侧颞叶结构的子区域之间，在处理新的对象身份和对象的新空间位置之间也存在功能上的分离。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号