...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The European Journal of Neuroscience >Functional connectivity between somatosensory and visual cortex in early blind humans.
【24h】

Functional connectivity between somatosensory and visual cortex in early blind humans.

机译：早期盲人的体感和视觉皮层之间的功能连接。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Abstract Crossmodal plasticity occurs when loss of input in one sensory modality leads to reorganization in brain representations of other sensory modalities. In congenital blindness the visual cortex becomes responsive to somatosensory input such as occurs during Braille reading. The route by which somatosensory information reaches the visual cortex is not known. Here, we used repetitive transcranial magnetic stimulation (rTMS) to probe the connection between primary somatosensory cortex (S1) and early visual cortex (V1 and neighboring areas), combining rTMS with positron emission tomography (PET). We applied stimulation over S1 in sighted, early blind and late blind individuals. Baseline regional cerebral blood flow in occipital cortex was highest in early blind and lowest in late blind individuals. Only the early blind group showed significant activation of early visual areas when rTMS was delivered over S1. This activation was significantly higher in early than in late blind, but not relative to sighted controls. These results are consistent with the hypothesis that tactile information may reach early visual areas in early blind humans through cortico-cortical pathways, possibly supporting enhanced tactile information processing.
机译：摘要当一种感觉模态的输入损失导致其他感觉模态的大脑表示重组时，就会发生跨模态可塑性。在先天性失明中，视觉皮层对诸如盲文阅读过程中发生的体感输入产生响应。体感信息到达视觉皮层的途径尚不清楚。在这里，我们使用重复经颅磁刺激（rTMS）来探究初级体感皮层（S1）与早期视觉皮层（V1和邻近区域）之间的联系，并将rTMS与正电子发射断层扫描（PET）结合起来。我们对有视力的，早期失明和晚期失明的人进行了S1刺激。枕叶的基线区域脑血流量在早期失明者中最高，而在晚期失明者中最低。当通过S1递送rTMS时，只有早期盲组显示出早期视觉区域的显着激活。这种激活在早期比在盲人晚期显着更高，但是相对于有视觉控制的人而言却不是。这些结果与假说触觉信息可以通过皮质-皮质途径到达早期盲人的早期视觉区域的假说相符，这可能支持增强的触觉信息处理。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号