...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The European Journal of Neuroscience >The clock in the dorsal suprachiasmatic nucleus runs faster than that in the ventral.
【24h】

The clock in the dorsal suprachiasmatic nucleus runs faster than that in the ventral.

机译：背上裂上核的时钟运行速度比腹侧的时钟快。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

In mammals, circadian rhythms are driven by a pacemaker located in the suprachiasmatic nuclei (SCN) of the hypothalamus. The pacemaker is composed of an ensemble of multiple, single-cell oscillators in the SCN. We measured arginine-vasopressin (AVP) release in organotypic SCN slices. The SCN slice culture showed circadian oscillation of AVP release with a period length (+/- SEM) of 23.84 +/- 00.03 h. This period is very similar to the one we previously reported in dispersed SCN cultures and is also close to that of behavioural rhythms. When the ventral part was removed by a surgical cut across the slice in the horizontal plane, however, the period became shorter (23.22 +/- 00.08 h). On the other hand, the removal of the dorsal part did not affect period length. These results suggest that the oscillators in ventral and dorsal cells contribute differently to period length and that the dorsal oscillators are entrained by the ventral ones to form a single integrated oscillator.
机译：在哺乳动物中，昼夜节律是由位于下丘脑上视交叉上核（SCN）的起搏器驱动的。起搏器由SCN中的多个单细胞振荡器组成。我们测量了器官型SCN切片中的精氨酸加压素（AVP）释放。 SCN切片培养物显示AVP释放的昼夜振荡，周期长度（+/- SEM）为23.84 +/- 00.03 h。这个时期与我们先前在分散的SCN文化中报道的时期非常相似，也与行为节律相近。但是，当通过外科手术在水平面上切开腹侧部分而将其切除时，该时间段变短了（23.22 +/- 00.08 h）。另一方面，背侧部分的切除不影响周期长度。这些结果表明，腹侧和背侧细胞中的振荡器对周期长度的贡献不同，并且背侧振荡器被腹侧振荡器带走以形成单个集成振荡器。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号