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首页> 外文期刊>The British Journal of Nutrition >Weight gain and insulin sensitivity: a role for the glycaemic index and dietary fibre?
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Weight gain and insulin sensitivity: a role for the glycaemic index and dietary fibre?

机译:体重增加和胰岛素敏感性:血糖指数和膳食纤维的作用?

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Since its first description by Jenkins et al in the 1980s, the glycaemic index (GI) has been used as a dietary tool to enhance the glycaemic control of people living with diabetes. The management of glycaemia is relevant today more than ever, with anestimated 2-9 million people currently affected by type 2 diabetes in the UK. However, the GI as a concept has dipped in and out of scientific fashion. By its nature, the GI is highly complex in that it hinges on a number of physico-chemical properties of carbohydrates, such as the chemical structure of the carbohydrate, the surrounding food matrix and the processing it undergoes. The fact that GI measurements are confounded by other food components within the diet serves as an additional layer of complexity. Consequently, the concept of the GI has been met, at times, with scepticism and some have found it challenging to embrace. However, one could argue that the proof is in the eating. There are now two high-quality systematic reviews that demonstratethe clinical utility of the GI in the management of type 2 diabetes, and a 24-week randomised controlled trial demonstrating a 0-5% fall in glycosylated Hb. There is also a Cochrane systematic review which suggests that the GI may play a role in promoting weight loss. Therefore, the literature, as it currently stands, presents a convincing case for the clinical application of the GI in the management of body weight and glucose homeostasis.
机译:自从Jenkins等人于1980年代首次描述血糖值以来,血糖指数(GI)已被用作饮食工具,以增强对糖尿病患者的血糖控制。如今,血糖的管理比以往任何时候都更加重要,英国目前估计有2-9百万人患有2型糖尿病。但是,地理标志作为一种概念已经浸入和脱离了科学时尚。就其性质而言,GI是高度复杂的,因为它取决于碳水化合物的许多物理化学特性,例如碳水化合物的化学结构,周围的食物基质及其经历的加工过程。饮食中的其他食物成分会混淆胃肠道测量的事实,这又增加了一层复杂性。因此,地理标志的概念有时会遭到怀疑,有些人认为难以接受。但是,有人可能会说证据就是饮食。现在有两项高质量的系统评价证明了GI在2型糖尿病的治疗中的临床应用,以及一项为期24周的随机对照试验,表明糖基化Hb下降了0-5%。 Cochrane的系统评价还表明,胃肠道可能在促进减肥中起作用。因此,目前的文献为胃肠道在体重和葡萄糖稳态管理中的临床应用提供了令人信服的案例。

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