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首页> 外文期刊>The British Journal of Nutrition >Consumption of a plant sterol-based spread derived from rice bran oil is effective at reducing plasma lipid levels in mildly hypercholesterolaemic individuals.
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Consumption of a plant sterol-based spread derived from rice bran oil is effective at reducing plasma lipid levels in mildly hypercholesterolaemic individuals.

机译：食用米糠油中的植物甾醇为基础的涂抹酱可有效降低轻度高胆固醇血症个体的血浆脂质水平。

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摘要

To establish the effectiveness of a new phytosterol-containing spread derived from rice bran oil (RBO), a randomised, double-blind, cross-over human clinical trial was conducted over 12 weeks. A total of eighty mildly hypercholesterolaemic (total blood cholesterol level >=5 and <=7.5 mmol/l with a serum TAG level of <=4.5 mmol/l) individuals were randomised into two groups (n 40). Group 1 consumed spread only daily for 4 weeks. They were randomised to consume 20 g RBO spread (RBOS), 20 g standard spread (SS) or 20 g phytosterol-enriched spread (PS). After a 4-week period, individuals changed to the next randomised treatment until all three treatments had been consumed. Group 2 consumed spread plus oil daily for 4 weeks. They consumed 20 g RBOS plus 30 ml RBO, 20 g SS plus 30 ml sunflower oil or 20 g RBOS. Blood samples were collected for the analysis of lipid parameters, and 3 d diet records were collected. Compared with SS, RBOS significantly reduced total cholesterol by 2.2% (P = 0.045), total cholesterol:HDL by 4.1% (P = 0.005) and LDL-cholesterol by 3.5% (P = 0.016), but was not as effective overall as PS, which reduced total cholesterol by 4.4% (P = 0.001), total cholesterol:HDL by 3.4% (P = 0.014) and LDL-cholesterol by 5.6% (P = 0.001). In group 2, the addition of RBO to the RBOS produced no differences in cholesterol levels. These results confirm that RBOS is effective in lowering serum cholesterol when consumed as part of a normal diet
机译：为了确定米糠油（RBO）衍生的含植物甾醇的新涂抹酱的功效，在12周内进行了一项随机，双盲，交叉的人类临床试验。总共80例轻度高胆固醇血症（总血胆固醇水平> = 5和<= 7.5 mmol / l，血清TAG水平<= 4.5 mmol / l）被随机分为两组（ n 40 ）。第一组消费仅每天传播4周。他们被随机摄入20 g RBO涂抹酱（RBOS），20 g标准涂抹酱（SS）或20 g富含植物甾醇的涂抹酱（PS）。在4周的时间后，个体将更改为下一个随机治疗，直到所有三种治疗均已消耗完为止。第2组每天食用涂抹酱和油，持续4周。他们食用了20克RBOS加30毫升RBO，20克SS加30毫升葵花籽油或20克RBOS。收集血样用于脂质参数分析，并收集3 d饮食记录。与SS相比，RBOS显着降低了总胆固醇2.2％（ P = 0.045），总胆固醇：HDL降低4.1％（ P = 0.005）和LDL-胆固醇3.5 ％（ P = 0.016），但总体效果不如PS，后者使总胆固醇降低了4.4％（ P = 0.001），总胆固醇：HDL降低了3.4％ （ P = 0.014）和LDL-胆固醇降低5.6％（ P = 0.001）。在第2组中，在RBOS中添加RBO对胆固醇水平没有影响。这些结果证实，作为正常饮食的一部分食用时，RBOS可有效降低血清胆固醇

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