Facile Three-Component Synthesis of Substituted Quinolines Catalyzed by Iridium(III)Complex

Takayuki Nakajima; Takashi Inada; Takeyuki Igarashi

首页> 外文期刊>Bulletin of the Chemical Society of Japan >Facile Three-Component Synthesis of Substituted Quinolines Catalyzed by Iridium(III)Complex

【24h】

Facile Three-Component Synthesis of Substituted Quinolines Catalyzed by Iridium(III)Complex

机译：铱（III）络合物催化取代喹啉的简易三组分合成

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

A convenient and efficient synthesis of substituted quinolines via a simple one-pot reaction of an aniline,an aromatic aldehyde,and an enolizable aliphatic aldehyde in the presence of the iridium catalyst [IrCl2H(cod)]2 under oxygen as an oxidant was developed.The reaction proceeds with Mannich-type imine formation followed by nucleophilic addition to give beta-amino aldehydes.Dehydrative cyclization takes place to give dihydroquinoline,which is then dehy-drogenated by aerobic oxidation to give 2-aryl-3-alkylquinolines.Dialkylquinolines were obtained by the reaction with anilines and aliphatic aldehydes in good yields.

机译：通过在氧作为氧化剂的铱催化剂[IrCl2H（cod）] 2存在下，通过苯胺，芳族醛和可烯化的脂族醛的简单一锅反应，开发了一种便捷高效的取代喹啉合成方法。反应进行到曼尼希型亚胺的形成，然后亲核加成，得到β-氨基醛。进行脱水环化得到二氢喹啉，然后通过有氧氧化将其脱氢，得到2-芳基-3-烷基喹啉，得到二烷基喹啉。与苯胺和脂族醛的反应，收率很高。

著录项

来源
《Bulletin of the Chemical Society of Japan》 |2006年第12期|共9页
作者
Takayuki Nakajima; Takashi Inada; Takeyuki Igarashi;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类化学;
关键词

相似文献

外文文献
中文文献
专利

1. Facile Three-Component Synthesis of Substituted Quinolines Catalyzed by Iridium(III)Complex [J] . Takayuki Nakajima, Takashi Inada, Takeyuki Igarashi Bulletin of the Chemical Society of Japan . 2006,第12期

机译：铱（III）络合物催化取代喹啉的简易三组分合成
2. Synthesis of Substituted Quinolines by Iron(III)-Catalyzed Three-Component Coupling Reaction of Aldehydes, Amines, and Styrenes [J] . Parthasarathy Gandeepan, P. Rajamalli, Chien-Hong Cheng Asian Journal of Organic Chemistry . 2014,第3期

机译：铁（III）催化的醛，胺和苯乙烯的三组分偶联反应合成取代的喹啉
3. IRIDIUM-CATALYZED REDISTRIBUTION OF HYDRODISILANES VIA A SILYL(SILYLENE)IRIDIUM(III) COMPLEX - SYNTHESIS OF A DONOR-STABILIZED SILYL(SILYLENE)IRIDIUM(III) COMPLEX [J] . Okazaki M., Ogino H., Tobita H. Chemistry Letters . 1997,第5期

机译：甲硅烷基（III）铱（III）配合物的铱催化的氢二硅烷的再分布-稳定化的硅烷（甲硅烷基）铱（III）配合物的合成
4. Synthesis of Substituted Quinolines by Iridium-Catalyzed Three Component Coupling Reaction [C] . Takashi Inada, Tadao Sekioka, Takeyuki Igarashi, Symposium on Organometallic Chemistry . 2004

机译：用铱催化三组分偶联反应合成取代的喹啉
5. I. Synthesis and reactivity of chiral iridium(III) and rhodium(III) complexes. II. Platinum-catalyzed iridium-methyl and iridium-phenyl bond formation [D] . Smith, Stuart Edward 2008

机译：I.手性铱（III）和铑（III）配合物的合成和反应性。二。铂催化的铱甲基和铱苯基键的形成
6. Facile Access to Fe(III)-Complexing Cyclic Hydroxamic Acids in a Three-Component Format [O] . Evgeny Chupakhin, Olga Bakulina, Dmitry Dar’in, 2019

机译：轻松获得三组分形式的复杂Fe（III）的环状异羟肟酸
7. Synthesis, molecular structure, and reactivity of Iridium(I) and Iridium(III) complexes formed by coordination and C−H activation of the substituted arenes C6H5CH2CH2PiPr2 and C6H5OCH2CH2PtBu2 [O] . Sola Eduardo, Martín Marta, Lahoz Fernando J., 2013

机译：通过取代芳烃C6H5CH2CH2PiPr2和C6H5OCH2CH2PtBu2的配位和CH活化形成的铱（I）和铱（III）配合物的合成，分子结构和反应性

Facile Three-Component Synthesis of Substituted Quinolines Catalyzed by Iridium(III)Complex

摘要

著录项

相似文献

相关主题

期刊订阅