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首页> 外文期刊>The British Journal of Nutrition >Tea and non-tea flavonol intakes in relation to atherosclerotic vascular disease mortality in older women.
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Tea and non-tea flavonol intakes in relation to atherosclerotic vascular disease mortality in older women.

机译：老年妇女中茶和非茶黄酮的摄入量与动脉粥样硬化性血管疾病的死亡率有关。

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摘要

Epidemiological studies have indicated that dietary flavonoids generally, and flavonols specifically, may contribute to cardiovascular health. Tea consumption, which is often the main dietary source of flavonoids and flavonols, is associated with a reduced risk of cardiovascular outcomes. The primary objective of the present study was to explore the association of the habitual intake of flavonols from tea and non-tea sources with the risk of atherosclerotic vascular disease mortality in a population of elderly women. A total of 1063 women, aged over 75 years, were randomly selected from ambulant Caucasian women living in Perth, Western Australia. Flavonoid consumption was assessed using the US Department of Agriculture Flavonoid, Flavone and Proanthocyanidin databases. Atherosclerotic vascular disease mortality was assessed over 5 years of follow-up through the Western Australian Data Linkage System. During the follow-up, sixty-four women died from atherosclerotic vascular disease. Women in the highest compared with the lowest tertile of flavonol intake had a lower risk of atherosclerotic vascular disease death (OR 0.27, 95% CI 0.13, 0.59; P<=0.01 for trend in multivariate-adjusted models). Similar relationships were observed for flavonol intake derived from both tea (OR 0.38, 95% CI 0.18, 0.79; P<0.01) and non-tea (OR 0.41, 95% CI 0.20, 0.85; P=0.05) sources. Tea was the main contributor to flavonol intake (65%), and the intakes of flavonols from tea and non-tea sources were not significantly correlated. In conclusion, increased consumption of flavonols was independently associated with a lower risk of atherosclerotic vascular disease mortality. Both tea and non-tea sources of flavonols were independently associated with this benefit.
机译：流行病学研究表明，饮食中的类黄酮，特别是类黄酮，可能有助于心血管健康。食用茶通常是类黄酮和黄酮的主要饮食来源，与降低心血管结局的风险有关。本研究的主要目的是探讨老年妇女中茶和非茶来源的黄酮醇的惯常摄入与动脉粥样硬化性血管病死亡风险的关系。从居住在西澳大利亚州珀斯市的高加索白人妇女中随机抽取了1063名年龄在75岁以上的妇女。使用美国农业部的类黄酮，黄酮和原花青素数据库评估了类黄酮的消费量。通过西澳大利亚数据链接系统对5年的随访评估了动脉粥样硬化性血管疾病的死亡率。在随访过程中，有64名妇女死于动脉粥样硬化性血管疾病。黄酮醇摄入量最高而最低的妇女中动脉粥样硬化性血管疾病死亡的风险较低（OR 0.27，95％CI 0.13，0.59;多变量校正模型中P <= 0.01）。对于从茶（OR 0.38，95％CI 0.18，0.79; P <0.01）和非茶（OR 0.41，95％CI 0.20，0.85; P = 0.05）来源中得到的黄酮醇摄入量也观察到相似的关系。茶是黄酮醇摄入量的主要来源（65％），并且茶和非茶源中黄酮醇的摄入量没有显着相关。总之，黄酮醇的消耗量增加与动脉粥样硬化性血管疾病死亡率降低的风险独立相关。黄酮醇的茶和非茶来源均独立地具有这种益处。

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