...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The British Journal of Nutrition >Effects of chromium-enriched Bacillus subtilis KT260179 supplementation on growth performance, caecal microbiology, tissue chromium level, insulin receptor expression and plasma biochemical profile of mice under heat stress
【24h】

Effects of chromium-enriched Bacillus subtilis KT260179 supplementation on growth performance, caecal microbiology, tissue chromium level, insulin receptor expression and plasma biochemical profile of mice under heat stress

机译：富铬枯草芽孢杆菌KT260179补充对热应激小鼠生长性能，盲肠微生物学，组织铬水平，胰岛素受体表达和血浆生化特性的影响

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The aim of this study was to investigate the effect of providing supplementary Cr-enriched Bacillus subtilis (CEBS) to mice with regard to their growth performance, caecal microbiology, tissue Cr concentration, insulin receptor (IR) expression and plasma biochemical profile. A total of ninety-six Kunming strain mice were allocated to four different groups: control, CEBS, inorganic Cr and B. subtilis. After 15 d of treatment, mice that received CEBS or normal B. subtilis had higher body weights than control mice, and after 30 d mice given either CEBS or B. subtilis had greater body weights than control mice or those given inorganic Cr. The concentration of Cr in tissues (heart, liver, spleen, kidney and skeletal muscle) increased after CEBS supplementation. B. subtilis and CEBS supplementation caused a significant increase in the numbers of Lactobacillus and Bifidobacterium in the caecum, whereas the numbers of Escherichia coli and Staphylococcus decreased significantly compared with the control. The levels of IR RNA and protein in skeletal muscles increased significantly. Plasma glucose, total cholesterol, TAG and LDL-cholesterol levels declined significantly in the CEBS group compared with the control group, whereas plasma insulin and HDL-cholesterol levels increased significantly. In conclusion, CEBS supplementation enhanced the regulation of body growth, increased tissue organic Cr concentrations, altered caecal microbiota and enhanced IR expression to produce significant changes in plasma biochemistry.
机译：这项研究的目的是调查向小鼠提供补充富铬的枯草芽孢杆菌（CEBS）的生长性能，盲肠微生物学，组织铬浓度，胰岛素受体（IR）表达和血浆生化特征的影响。将总共​​九十六只昆明品系小鼠分为四个不同的组：对照组，CEBS，无机铬和枯草芽孢杆菌。治疗15天后，接受CEBS或正常枯草芽孢杆菌的小鼠的体重高于对照小鼠，接受CEBS或枯草芽孢杆菌的30 d小鼠的体重高于对照小鼠或接受无机铬的小鼠。补充CEBS后，组织（心脏，肝脏，脾脏，肾脏和骨骼肌）中的Cr浓度增加。枯草芽孢杆菌和CEBS的添加导致盲肠中乳酸杆菌和双歧杆菌的数量显着增加，而大肠杆菌和葡萄球菌的数量与对照组相比明显减少。骨骼肌中IR RNA和蛋白质的水平显着增加。与对照组相比，CEBS组的血浆葡萄糖，总胆固醇，TAG和LDL-胆固醇水平显着下降，而血浆胰岛素和HDL-胆固醇水平显着上升。总之，CEBS补充剂增强了机体生长的调节，增加了组织中有机Cr的浓度，改变了盲肠微生物区系，并增强了IR表达，从而在血浆生化中产生了显着变化。

著录项

相似文献

  • 外文文献
  • 中文文献
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号