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首页> 外文期刊>The Canadian Journal of Neurological Sciences: le Journal Canadien des Sciences Neurologiques >Prevalence of multiple sclerosis in First Nations people of Alberta.
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Prevalence of multiple sclerosis in First Nations people of Alberta.

机译：艾伯塔省原住民多发性硬化症的患病率。

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BACKGROUND: Multiple Sclerosis (MS) is reported to be uncommon among North American aboriginals despite frequent intermarriage with people of European ancestry, but few population-based studies have been conducted. The purpose of this study was to determine the prevalence of MS among First Nations aboriginal people in Alberta, Canada compared to the general population. METHODS: All hospital in-patient and physician fee-for-service records between 1994 and 2002 where a diagnosis of MS was mentioned were extracted from government health databases in the province of Alberta. First Nations people can be identified since the federal government (Health Canada) pays health care insurance premiums on their behalf. Multiple Sclerosis prevalence per 100,000 population for both First Nations people and the general population of Alberta were calculated for each year during this time span. RESULTS: Among First Nations in Alberta, MS prevalence was 56.3 per 100,000 in 1994 and 99.9 per 100,000 in 2002, an increase of 43.6%. In 2002 prevalence was 158.1 and 38.0 for females and males respectively, a female to male ratio of 4.2:1. Multiple Sclerosis prevalence among the general population of Alberta was 262.6 per 100,000 in 1994 and 335.0 per 100,000 in 2002, an increase of 21.6%. In 2002 prevalence was 481.5 and 187.5 for females and males respectively, a female to male ratio of 2.6:1. Peak prevalence for both First Nations and general population females in 2002 was age 50-59, also 50-59 for both First Nations and general population males. CONCLUSION: While MS prevalence in First Nations people is lower than in the general population of Alberta, it is not rare by worldwide standards.
机译：背景：尽管与欧洲血统的人经常通婚，据报道在北美原住民中多发性硬化症（MS）并不常见，但很少进行基于人群的研究。本研究的目的是确定与普通人群相比，加拿大艾伯塔省原住民原住民的MS患病率。方法：从艾伯塔省的政府卫生数据库中提取1994年至2002年之间所有提及MS诊断的医院住院和医师收费记录。由于联邦政府（加拿大卫生部）代表他们支付医疗保险费，因此可以确定原住民。在此时间段内，每年计算出原住民和艾伯塔省总人口的每10万人口多发性硬化症患病率。结果：在艾伯塔省的原住民中，MS患病率在1994年为100,000的56.3，而在2002年为100,000的99.9。 2002年，女性和男性的患病率分别为158.1和38.0，男女之比为4.2：1。 1994年艾伯塔省普通人群中的多发性硬化症患病率为262.6 / 10万，2002年为335.0 / 10万，增长了21.6％。 2002年，男女患病率分别为481.5和187.5，男女之比为2.6：1。 2002年，原住民和普通人口女性的最高流行率是50-59岁，原住民和普通人口男性的最高流行率是50-59岁。结论：虽然原住民的MS患病率低于艾伯塔省的总人口，但按世界范围的标准并不罕见。

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