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首页> 外文期刊>The Canadian Journal of Neurological Sciences: le Journal Canadien des Sciences Neurologiques >Cine phase-contrast MR images failed to predict clinical outcome following ETV.
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Cine phase-contrast MR images failed to predict clinical outcome following ETV.

机译：电影相衬MR图像无法预测ETV后的临床结局。

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摘要

BACKGROUND: To predict success of endoscopic third ventriculostomy (ETV) in patients with obstructive hydrocephalus, we evaluated pre- and post- operative phase-contrast cine magnetic resonance images (PC MRI) on cerebrospinal fluid (CSF), cine flow in basal cisterns around the brain stem, and cervical medullar junction (CMJ) retrospectively. METHODS: The study involved 102 patients with mean age of 36.74+/-23.25, and F/M = 1.55. All patients had PC MRI taken both pre- and post-operatively. A dynamic MRI video of PC MRI was reviewed at sagittal, axial, and coronal sections to determine cistern flows around the brain stem and CMJ. For quantitative analysis, quadrants were divided around midbrain axially to evaluate interpeduncular, quadrageminal, and ambient cisterns of both sides using scores of 0 to 60. Pre- and post- pontine and CMJ flows were shown in sagittal view and scored 0 to 20, and lateral cerebellopontine cisterns of both sides were measured on coronal image and scored 0 to 20. RESULTS: No significant difference in CSF flow was seen from three individual views and total cine score, or between ETV success and failure groups by multivariate analysis of variance. Kaplan-Meier Analysis and Spearman's Correlation Test produced no relationship between MRI cine flow scores and interval period after surgery to ETV failure. CONCLUSION: PC MRI cine flow failed to demonstrate significant differences between successful and failed ETV groups. This indicates in addition to achieving an adequate fenestration, CSF pathways beyond the basal cisterns around the brain stem and CMJ may play an essential role in achieving ETV success.
机译：背景：为了预测内窥镜第三脑室造口术（ETV）在梗阻性脑积水患者中的成功，我们评估了脑脊液（CSF）的术前和术后相衬电影磁共振图像（PC MRI），基础池周围的电影流脑干和颈髓交界处（CMJ）进行回顾性研究。方法：该研究纳入102例平均年龄为36.74 +/- 23.25，F / M = 1.55的患者。所有患者在术前和术后均进行了PC MRI检查。对PC MRI的动态MRI视频进行了矢状，轴向和冠状切面检查，以确定脑干和CMJ周围的水箱流量。为了进行定量分析，将象限沿轴向围绕中脑进行划分，以使用0到60的分数评估两侧的椎间，四肢和周围的储水池。以矢状面显示桥前和后的CMJ流量，并以0到20的分数表示。在冠状位图像上测量了两侧的小脑桥小脑外侧水箱，得分为0到20。结果：通过多变量方差分析，从三个个人观点和总电影评分，或在ETV成功与失败组之间，CSF血流没有显着差异。 Kaplan-Meier分析和Spearman相关检验在ETV失败的手术后MRI电影流量评分与间隔时间之间没有关系。结论：PC MRI电影流未能证明成功和失败的ETV组之间存在显着差异。这表明，除了获得足够的开窗率外，脑干和CMJ周围的基底池以外的CSF通路可能在实现ETV成功方面也起着至关重要的作用。

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