• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The Canadian Journal of Neurological Sciences: le Journal Canadien des Sciences Neurologiques >Development of a concise QOL questionnaire for brain tumor patients.
【24h】

Development of a concise QOL questionnaire for brain tumor patients.

机译：为脑肿瘤患者开发简洁的QOL调查表。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BACKGROUND: The purpose of this study was to develop and validate a self-administered questionnaire to measure the health-related quality of life (QOL) of patients with brain cancer. We wanted to assess both core and disease-specific concerns in a single, easy-to-use instrument, thus promoting concision and clinical utility. The questionnaire departs from its predecessors in that it was designed for- and validated among French speaking Canadians. METHODS: A focus group of health professionals was used to develop items for the questionnaire, which was later validated with 105 patients suffering from brain cancer. The underlying structure of the questionnaire was investigated using principal component analysis and confirmed using a principal factor analysis. RESULTS: The final version of the questionnaire contains 30 items. Seven multi-item scales, tapping into distinct dimensions of QOL, were uncovered (i.e., functional well-being, symptom severity/fear of death, social support/acceptance of disease, autonomy in personal care, digestive symptomatology, neurocognitive function, and pain). Assessment of reliability revealed elevated internal consistency for each of the seven scales (Cronbach coefficient alpha .65), whereas known-groups validity (anchor-based approach) revealed that the different dimensions uniquely discriminated between patients with different functional levels (Karnofsky Performance Scores) and clinical status (exposure to neurosurgery, radiotherapy, and use of chemotherapy and anticonvulsants). CONCLUSION: Our QOL questionnaire, the Sherbrooke Neuro-Oncology Assessment Scale, or SNAS, taps into both core and disease-specific issues relevant to neuro-oncology patients. It has good validity and reliability, and clearly reflects the multidimensional nature of QOL. Depending on the research focus, it may be used in clinical trials to track the impact of disease and/or treatment on satisfaction, functional status, and general well-being.
机译：背景：本研究的目的是开发和验证一种自行管理的问卷，以测量脑癌患者的健康相关生活质量（QOL）。我们希望在一台易于使用的仪器中评估核心和疾病特定问题，从而提高简洁性和临床实用性。该调查表与之前的调查表不同，它是专为讲法语的加拿大人设计并经过验证的。方法：由卫生专业人员组成的焦点小组制定了调查表的项目，随后对105名患有脑癌的患者进行了验证。使用主成分分析调查问卷的基础结构，并使用主因子分析进行确认。结果：问卷的最终版本包含30个项目。发现了七个针对多方面生活质量的多项目量表（即功能性幸福感，症状严重程度/对死亡的恐惧，社会支持/疾病的接受程度，个人护理的自主性，消化系统症状，神经认知功能和疼痛） ）。可靠性评估显示，七个量表中的每个量表均具有较高的内部一致性（Cronbach系数α.65），而已知群体的有效性（基于锚的方法）显示，不同功能水平的患者之间的唯一区别是独特的（卡诺夫斯基绩效评分）和临床状态（接受神经外科手术，放射疗法以及使用化学疗法和抗惊厥药）。结论：我们的QOL调查问卷，Sherbrooke神经肿瘤评估量表或SNAS涉及与神经肿瘤患者相关的核心问题和特定于疾病的问题。它具有良好的有效性和可靠性，并且清楚地反映了QOL的多维性质。根据研究重点，可以在临床试验中使用它来跟踪疾病和/或治疗对满意度，功能状态和总体健康的影响。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号