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首页> 外文期刊>The Canadian Journal of Neurological Sciences: le Journal Canadien des Sciences Neurologiques >A case of amiodarone-associated myoclonus responsive to levetiracetam.
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A case of amiodarone-associated myoclonus responsive to levetiracetam.

机译：一例胺碘酮相关的对左乙拉西坦有反应的肌阵挛。

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摘要

Amiodarone, a class III antiarrhythmic, is infrequently associated with neurotoxicity. Reported adverse events include peripheral neuropathy, tremor, ataxia, parkinsonism and cognitive impairment. We report a case of a patient with amiodarone-associated myoclonus.A 90-year-old man with mild dementia presented with involuntary jerks and impaired gait. Past medical history was significant for chronic renal insufficiency, coronary artery disease, aortic valve replacement, and automated defibrillator placement. His chronic renal insufficiency was first diagnosed as ; a young adult, but his creatinine, although elevated, had remained stable for years without the need for hemodialysis. Two years prior to presentation, the patient was prescribed the antiarrhythmics digoxin and amiodarone.
机译：胺碘酮（III类抗心律不齐）很少与神经毒性相关。报告的不良事件包括周围神经病变，震颤，共济失调，帕金森氏症和认知障碍。我们报告了一例胺碘酮相关性肌阵挛的患者。一名90岁的轻度痴呆患者出现了不自主的抽搐和步态障碍。过去的医学史对于慢性肾功能不全，冠状动脉疾病，主动脉瓣置换和自动除颤器置入具有重要意义。他的慢性肾功能不全首先被诊断为;一位年轻的成年人，但他的肌酐虽然升高，但多年来一直保持稳定，无需进行血液透析。在就诊前两年，给患者开了抗心律不齐地高辛和胺碘酮的处方。

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