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首页> 外文期刊>The Canadian Journal of Neurological Sciences: le Journal Canadien des Sciences Neurologiques >Cerebral amyloid angiopathy presenting with TIA-like episodes.
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Cerebral amyloid angiopathy presenting with TIA-like episodes.

机译：脑淀粉样血管病，表现为TIA样发作。

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摘要

Cerebral amyloid angiopathy (CAA) is a common age-related cerebral small vessel disease characterized by a progressive deposition of amyloid-beta in the wall of cortical and leptomeningeal small arteries, with or without capillary involvement. It is a frequent cause of spontaneous intracerebral hemorrhage and cognitive impairment in the elderly. Another characteristic clinical presentation associated with CAA is transient focal neurological episode (TFNE). As recently reported, TFNE could be divided into a positive-symptoms form (aura-like) and a negative-symptoms form (transient ischemic attack-like). We present a case of probable cerebral amyloid angiopathy presenting with transient ischemic attack-like episodes. A 69-year-old Caucasian man was admitted to the emergency department because of acute onset right arm weakness and speech impairment, lasting 30 minutes. A computed tomogram (CT) brain scan showed leukoaraiosis and mild cortical atrophy. The patient complained of a similar episode one day before. He was a smoker and moderate alcohol drinker; he had referred with higher blood pressure and mild carotid atherosclerosis for two years. He was taking ramipril, aspirin 100 mg and low-dose statin. ABCD2 score was moderate.
机译：脑淀粉样血管病（CAA）是一种常见的与年龄相关的脑小血管疾病，其特征是β-淀粉样蛋白逐渐沉积在皮层和小脑膜小动脉壁中，伴有或不伴有毛细血管受累。它是老年人自发性脑出血和认知障碍的常见原因。与CAA相关的另一种典型临床表现是短暂性局灶性神经系统发作（TFNE）。正如最近报道的那样，TFNE可以分为阳性症状形式（先兆样）和阴性症状形式（短暂性缺血发作样）。我们提出一例可能出现短暂性脑缺血发作样发作的脑淀粉样血管病。一名69岁的白人男子因右臂无力急性发作和语言障碍而被送往急诊室，持续30分钟。电脑断层扫描（CT）脑部扫描显示出白斑病和轻度皮质萎缩。该患者前一天也有类似的发作。他是一个吸烟者，适度饮酒。他转诊高血压和轻度颈动脉粥样硬化两年。他正在服用雷米普利，阿司匹林100毫克和低剂量他汀类药物。 ABCD2评分为中度。

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