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首页> 外文期刊>The Canadian Journal of Neurological Sciences: le Journal Canadien des Sciences Neurologiques >Brain metastasis from prostate small cell carcinoma: not to be neglected.
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Brain metastasis from prostate small cell carcinoma: not to be neglected.

机译：前列腺小细胞癌的脑转移：不可忽视。

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摘要

BACKGROUND: Symptomatic brain metastases from prostatic carcinoma are rare (0.05% to 0.5%). CASE REPORT: A 70-year-old man presented with a homonymous hemianopsia due to brain metastatic prostatic carcinoma shortly before becoming symptomatic of prostatic disease. CT and MRI of the brain showed a tumour deep in the right hemisphere near the thalamus and involving the optic radiation. RESULTS: Routine haematological and biochemical tests were normal. The prostate specific antigen level was low on two separate occasions. The prostatic and brain tumours showed identical appearances, namely of a poorly differentiated adenocarcinoma with neuroendocrine differentiation (small cell carcinoma). CONCLUSION: A literature review suggests that small cell carcinoma of the prostate is more likely to spread to the brain compared to adenocarcinoma and that brain metastases indicate a poor prognosis. The prostate gland should be remembered as a possible cause of brain metastases and that a normal serum prostate specific antigen does not exclude this diagnosis.
机译：背景：前列腺癌的症状性脑转移很少见（0.05％至0.5％）。病例报告：一名70岁的男子在成为前列腺疾病的症状之前不久因脑转移性前列腺癌而出现了同名偏盲症。脑部的CT和MRI显示，在靠近丘脑的右半球深处有一个肿瘤，累及了光辐射。结果：常规血液学和生化检查正常。在两次不同的情况下，前列腺特异性抗原水平较低。前列腺肿瘤和脑肿瘤的外观相同，即具有神经内分泌分化的低分化腺癌（小细胞癌）。结论：文献综述表明，与腺癌相比，前列腺小细胞癌更可能扩散到大脑，并且脑转移表明预后不良。应当记住前列腺是脑转移的可能原因，并且正常的血清前列腺特异性抗原不能排除这种诊断。

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