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Stressful life events preceding the onset of depression in Asian patients with major depressive disorder

机译:亚洲重度抑郁症患者抑郁发作前的紧张生活事件

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Background: Previous studies have identified the significant role of stressful life events in the onset of depressive episodes. However, there is a paucity of cross-national studies on stressful life events that precede depression. Aims: We aimed to compare types of stressful life events associated with the onset of depressive episodes in patients with major depressive disorder (MDD) in five Asian countries. Method: A total of 507 outpatients with MDD were recruited in China (n = 114), South Korea (n = 101), Malaysia (n = 90), Thailand (n = 103) and Taiwan (n = 99). All patients were assessed with the Mini-International Neuropsychiatric Interview and the List of Threatening Experiences. The prevalence of each type of stressful life events was calculated and compared between each country. Results: The type of stressful life event that preceded the onset of a depressive episode differed between patients in China and Taiwan and those in South Korea, Malaysia and Thailand. Patients in China and Taiwan were less likely to report interpersonal relationship problems and occupational/financial problems than patients in South Korea, Malaysia and Thailand. Conclusion: Understanding the nature and basis of culturally determined susceptibilities to specific stressful life events is critical for establishing a policy of depression prevention and providing effective counseling services for depressed patients.
机译:背景:以前的研究已经确定了应激性生活事件在抑郁发作中的重要作用。但是,对于抑郁症之前的压力性生活事件的跨国研究很少。目的:我们旨在比较五个亚洲国家重度抑郁症(MDD)患者与抑郁发作相关的应激性生活事件的类型。方法:在中国(n = 114),韩国(n = 101),马来西亚(n = 90),泰国(n = 103)和台湾(n = 99)共招募了507名MDD门诊患者。所有患者均接受了迷你国际神经精神病学访谈和威胁经历清单评估。计算了每种类型的压力性生活事件的发生率,并在每个国家之间进行了比较。结果:抑郁症发作之前的应激性生活事件类型在中国和台湾的患者以及韩国,马来西亚和泰国的患者之间有所不同。与韩国,马来西亚和泰国的患者相比,中国和台湾的患者报告人际关系问题和职业/财务问题的可能性较小。结论:了解文化确定的对特定压力性生活事件的敏感性的性质和基础,对于制定预防抑郁的政策和为抑郁患者提供有效的咨询服务至关重要。

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