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首页> 外文期刊>The International journal of social psychiatry >Two-year follow-up of borderline personality disorder patients in Italy: a preliminary report on prognosis and prediction of outcome.
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Two-year follow-up of borderline personality disorder patients in Italy: a preliminary report on prognosis and prediction of outcome.

机译：意大利边缘性人格障碍患者的两年随访：关于预后和预后的初步报告。

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BACKGROUND and AIMS: Few naturalistic studies have examined the course of borderline personality disorder (BPD) outside North American countries. The aim of this prospective study was to investigate remission rate, changes in the level of BPD psychopathology and outcome prediction in a sample (n = 46) of Italian BPD outpatients over a two-year follow-up. METHOD: Two years after baseline, remission rate from BPD and changes in the severity of BPD psychopathology were investigated. Initial measures of borderline, comorbid Axis I and II psychopathology and clinical severity, as well as historical and socio-demographic variables, were used to predict the number of BPD criteria met at follow-up. RESULTS: At the two-year interview, the mean number of BPD criteria endorsed decreased ( p = 0.04) and 12 participants (26.1%) fell below the diagnostic threshold for BPD. Borderline psychopathology at follow-up was predicted by the presence, at baseline, of substance use disorders and self-defeating personality traits, and by the absence of dependent traits (R(2) = 0.409; p < 0.001). However, these results cannot be generalized to patients lost to follow-up (15 out of an initial sample of 61), who may exhibit a more severe psychopathology at baseline and therefore a poorer prognosis. CONCLUSIONS: Borderline individuals seeking treatment at Italian public psychiatric centres may show some improvement in BPD psychopathology over a two-year follow-up; however, the remission rate seems to be lower than that found in North American samples. Furthermore, outcome predictors overlap only partially with those detected by North American studies.
机译：背景和目的：很少有自然研究研究北美国家以外的边缘性人格障碍（BPD）的过程。这项前瞻性研究的目的是调查意大利BPD门诊患者的样本（n = 46），为期两年，随访期缓解率，BPD精神病理学水平的变化和结果预测。方法：基线后两年，调查了BPD的缓解率和BPD精神病理学严重程度的变化。初步测量边界线，合并的I，II轴精神病理学和临床严重程度，以及历史和社会人口统计学变量，用于预测随访时符合的BPD标准数量。结果：在为期两年的访谈中，认可的BPD标准平均数下降了（p = 0.04），有12名参与者（26.1％）低于BPD的诊断阈值。基线时存在药物滥用障碍和自我败坏的人格特质，以及不存在依赖性特质，可预测随访时的临界心理病理学（R（2）= 0.409; p <0.001）。但是，这些结果不能推广到失去随访的患者（61名初始样本中有15名），他们可能在基线时表现出更严重的精神病理学，因此预后较差。结论：在两年的随访中，在意大利公共精神病学中心寻求治疗的边缘人群可能会表现出BPD精神病理学的一些改善。但是，其缓解率似乎低于北美样品。此外，结果预测变量仅与北美研究发现的部分重叠。

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