CARRIERS OF THE COMT MET/MET ALLELE HAVE HIGHER DEGREES OF HYPNOTIZABILITY, PROVIDED THAT THEY HAVE GOOD ATTENTIONAL CONTROL: A Case of Gene-Trait Interaction

Rominger Christian; Weiss Elisabeth M.; Nagl Simone; Niederstaetter Harald; Parson Walther; Papousek Ilona

首页> 外文期刊>The International journal of clinical and experimental hypnosis >CARRIERS OF THE COMT MET/MET ALLELE HAVE HIGHER DEGREES OF HYPNOTIZABILITY, PROVIDED THAT THEY HAVE GOOD ATTENTIONAL CONTROL: A Case of Gene-Trait Interaction

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CARRIERS OF THE COMT MET/MET ALLELE HAVE HIGHER DEGREES OF HYPNOTIZABILITY, PROVIDED THAT THEY HAVE GOOD ATTENTIONAL CONTROL: A Case of Gene-Trait Interaction

机译：MET / MET等位基因的携带者具有更高的催眠度，条件是他们具有良好的注意力控制：一个基因特质相互作用的案例

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Genetic factors may explain part of the interindividual variability in hypnotizability. A new avenue that may provide more comprehensive understanding of the phenotypic effects of genetic variations is the study of gene-trait interaction. In this study, the authors investigate the relationship of the dopamine-related COMT and the serotonin-related 5-HTTLPR polymorphisms to hypnotizability by taking individual differences in executive attention into account. Homozygosity for the COMT Met allele, putatively linked to the capability or proneness to dissociate from reality, was associated with high hypnotizability only if paired with high-attention ability. The finding can be integrated into hypnosis theory and represents a case of gene-trait interaction suggesting that investigating the effects of a gene in the context of relevant psychological traits may further elucidate gene-brain-behavior relationships.

机译：遗传因素可能解释了催眠作用的部分个体差异。可以提供对遗传变异的表型效应更全面理解的新途径是对基因-性状相互作用的研究。在这项研究中，作者研究了多巴胺相关的COMT和5-羟色胺相关的5-HTTLPR多态性与催眠性之间的关系，方法是考虑到执行者注意的个体差异。假定与COMT Met等位基因的纯合性相关联或倾向于脱离现实的能力，只有与高注意力能力配对时，才具有高催眠作用。这一发现可以被整合到催眠理论中，并代表了一个基因-性格相互作用的案例，表明在相关心理性状的背景下研究一个基因的作用可能会进一步阐明基因-脑-行为的关系。

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《The International journal of clinical and experimental hypnosis》 |2014年第4期|共28页
作者
Rominger Christian; Weiss Elisabeth M.; Nagl Simone; Niederstaetter Harald; Parson Walther; Papousek Ilona;
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正文语种 eng
中图分类神经病学与精神病学;
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1. CARRIERS OF THE COMT MET/MET ALLELE HAVE HIGHER DEGREES OF HYPNOTIZABILITY, PROVIDED THAT THEY HAVE GOOD ATTENTIONAL CONTROL: A Case of Gene-Trait Interaction [J] . Rominger Christian, Weiss Elisabeth M., Nagl Simone, The International journal of clinical and experimental hypnosis . 2014,第4期

机译：MET / MET等位基因的携带者具有更高的催眠度，条件是他们具有良好的注意力控制：一个基因特质相互作用的案例
2. The met158 allele of catechol-O-methyltransferase (COMT) is associated with obsessive-compulsive disorder in men: case|[ndash]|control study and meta-analysis [J] . E C Pooley, N Fineberg, P J Harrison Molecular Psychiatry . 2007,第6期

机译：儿茶酚-O-甲基转移酶（COMT）的met158等位基因与男性强迫症有关：病例|对照|荟萃分析
3. The enzymatic activities of brain catechol-O-methyltransferase (COMT) and methionine sulphoxide reductase are correlated in a COMT Val/Met allele-dependent fashion [J] . Moskovitz J., Walss-Bass C., Cruz D. A., Neuropathology and applied neurobiology . 2015,第7期

机译：脑儿茶酚-O-甲基转移酶（COMT）和蛋氨酸亚砜还原酶的酶活性以COMT Val / Met等位基因依赖的方式相关
4. Research on Multilevel Inverter Carrier-Based PWM Method Based on Control Degrees of Freedom Combination [C] . Hongyan Wang, Xiangning He, Rongxiang Zhao International PCIM China Conference on Power Electronics; 20030312-14; Shanghai(CN) . 2003

机译：基于自由度组合度的基于多电平逆变器载波的PWM方法研究
5. COMT mediated methylation metabolism of equine estrogen metabolite: 4-hydroxyequilenin. [D] . Li, Yan. 2005

机译：COMT介导的马雌激素代谢物：4-羟基e烯素的甲基化代谢。
6. Hypnotizability and Catechol-O-Methyltransferase (COMT) polymorphysms in Italians [O] . Silvano Presciuttini, Alessandro Gialluisi, Serena Barbuti, 2013

机译：意大利人的催眠性和邻苯二酚-O-甲基转移酶（COMT）多态性
7. The met(158) allele of catechol-O-methyltransferase (COMT) is associated with obsessive-compulsive disorder in men: case-control study and meta-analysis. [O] . Pooley, EC, Fineberg, N, Harrison, PJ 2007

机译：儿茶酚-O-甲基转移酶（COMT）的met（158）等位基因与男性强迫症相关：病例对照研究和荟萃分析。

CARRIERS OF THE COMT MET/MET ALLELE HAVE HIGHER DEGREES OF HYPNOTIZABILITY, PROVIDED THAT THEY HAVE GOOD ATTENTIONAL CONTROL: A Case of Gene-Trait Interaction

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