Sclerotome development and morphogenesis: when experimental embryology meets genetics

Monsoro-Burq AH

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Sclerotome development and morphogenesis: when experimental embryology meets genetics

机译：巩膜刀的发育和形态发生：当实验胚胎学与遗传学相遇时

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The vertebra develops from the ventral part of the somite, the sclerotome. Sclerotome progenitors are subject to multiple signaling molecules secreted by the adjacent tissues that control their fate. The aim of this article is to discuss the mechanisms of sclerotome induction, chondrogenesis and morphogenesis. By integrating the results from classical studies and recent molecular advances, this will illustrate how the powerful combination of experimental embryology and genetic approaches has recently illuminated the multiple steps of vertebra formation.

机译：脊椎从躯体的腹侧部分（硬骨刀）发育而来。菌核组祖细胞受到控制其命运的相邻组织分泌的多种信号分子的影响。本文的目的是讨论硬核刀诱导，软骨形成和形态发生的机制。通过整合经典研究和最新分子研究的结果，这将说明实验胚胎学和遗传学方法的强大结合如何最近阐明了椎骨形成的多个步骤。

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《The international journal of developmental biology》 |2005年第3期|共8页
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Monsoro-Burq AH;
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正文语种 eng
中图分类普通胚胎学;
关键词
sclerotome; BMP; sonic hedgehog; Nkx3.2; Pax; Msx; Sox9; VERTEBRAL COLUMN DEVELOPMENT; SONIC-HEDGEHOG; NEURAL-TUBE; FLOOR PLATE; AVIAN EMBRYOS; SPINAL-CORD; CHICK-EMBRYO; SOMITIC CHONDROGENESIS; PARAXIAL MESODERM; SOMITOCOELE CELLS;

机译：菌群;BMP;声波刺猬;Nkx3.2;Pax;Msx;Sox9;椎骨发育;超声-刺猬;神经管;地板;禽类胚胎;脊髓线束;鸡胚;交感软骨细胞;旁突细胞;

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7. Sclerotome development and morphogenesis: when experimental embryology meets genetics. [O] . Monsoro-Burq, Anne Hélène 2004

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Sclerotome development and morphogenesis: when experimental embryology meets genetics

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