Staphylococcal protein A-formulated immune complexes suppress enterotoxin-induced cellular responses in nasal polyps

Okano Mitsuhiro; Fujiwara Tazuko; Kariya Shin; Haruna Takenori; Higaki Takaya; Noyama Yasuyuki; Makihara Sei-ichiro; Kanai Kengo; Nishizaki Kazunori

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Staphylococcal protein A-formulated immune complexes suppress enterotoxin-induced cellular responses in nasal polyps

机译：葡萄球菌蛋白A配制的免疫复合物抑制肠毒素诱导的鼻息肉细胞反应

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Background: Recent studies have revealed that Staphylococcus aureus and its components participate in the pathogenesis of eosinophilic airway diseases, such as chronic rhinosinusitis with nasal polyps.

机译：背景：最近的研究表明，金黄色葡萄球菌及其成分参与了嗜酸性气道疾病的发病机理，例如患有鼻息肉的慢性鼻-鼻窦炎。

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《The Journal of Allergy and Clinical Immunology》 |2015年第2期|共16页
作者
Okano Mitsuhiro; Fujiwara Tazuko; Kariya Shin; Haruna Takenori; Higaki Takaya; Noyama Yasuyuki; Makihara Sei-ichiro; Kanai Kengo; Nishizaki Kazunori;
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正文语种 eng
中图分类医学免疫学;
关键词
Chronic rhinosinusitis with nasal polyps; cytokines; enterotoxins; immune complexes; immunoglobulins; immune evasion; Staphylococcus aureus; staphylococcal protein A;

机译：慢性鼻鼻窦炎伴鼻息肉;细胞因子;肠毒素;免疫复合物;免疫球蛋白;免疫逃逸;金黄色葡萄球菌;葡萄球菌蛋白A;

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1. Staphylococcal protein A-formulated immune complexes suppress enterotoxin-induced cellular responses in nasal polyps [J] . Okano Mitsuhiro, Fujiwara Tazuko, Kariya Shin, The Journal of Allergy and Clinical Immunology . 2015,第2期

机译：葡萄球菌蛋白A配制的免疫复合物抑制肠毒素诱导的鼻息肉细胞反应
2. Regulatory effect of TLR3 signaling on staphylococcal enterotoxin-induced IL-5, IL-13, IL-17A and IFN-γ production in chronic rhinosinusitis with nasal polyps [J] . Mitsuhiro Okano, Tazuko Fujiwara, Shin Kariya, Allergology international: official journal of the Japanese Society of Allergology . 2016,第1期

机译：TLR3信号转导对慢性鼻鼻窦炎鼻息肉中葡萄球菌肠毒素诱导的IL-5，IL-13，IL-17A和IFN-γ产生的调节作用
3. Chronic sinusitis with nasal polyps: staphylococcal exotoxin immunoglobulin E and cellular inflammation. [J] . Conley DB, Tripathi A, Ditto AM, American journal of rhinology . 2004,第5期

机译：慢性鼻窦炎伴鼻息肉：葡萄球菌外毒素免疫球蛋白E和细胞炎症。
4. Signal Pathway in Sinusitis, Polyps and Normal Nasal Mucosa through Bioinformatics Analysis on Differentially Expressed-Proteins [C] . Chen, Xuedong, Tang, Faqing, Sun, Hong International Conference on Biomedical Engineering and Informatics;BMEI '09 . 2009

机译：通过差异表达蛋白的生物信息学分析鼻窦炎，息肉和正常鼻黏膜的信号通路
5. Role of the Vaccinia Virus E3 protein and its poxvirus orthologues in suppressing innate immune responses activated by RNA-based pathogen-associated molecular patterns. [D] . Myskiw, Chad. 2012

机译：牛痘病毒E3蛋白及其痘病毒直向同源物在抑制先天免疫应答中的作用，该先天免疫应答是由基于RNA的病原体相关分子模式激活的。
6. Cellular responses to Staphylococcus aureus alpha-toxin are associated with clinical outcomes in chronic rhinosinusitis with nasal polyps [O] . Mitushiro Okano, Takenori Haruna, Yasuyuki Noyama, 2013

机译：细胞对金黄色葡萄球菌α-毒素的反应与慢性鼻-鼻窦炎鼻息肉的临床结果相关
7. Regulatory effect of TLR3 signaling on staphylococcal enterotoxin-induced IL-5, IL-13, IL-17A and IFN-γ production in chronic rhinosinusitis with nasal polyps [O] . Okano, Mitsuhiro, Fujiwara, Tazuko, Kariya, Shin, 2016

机译：TLR3信号转导对慢性鼻鼻窦炎鼻息肉中葡萄球菌肠毒素诱导的IL-5，IL-13，IL-17A和IFN-γ产生的调节作用

Staphylococcal protein A-formulated immune complexes suppress enterotoxin-induced cellular responses in nasal polyps

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